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Internal Medicine - Diagnostics:

DateRef. No.Patent No.Title
11/9/2009E-012-2009/0A Method of Identifying Cdk5/p35 Modulators, and Possible Diagnostic or Therapeutic Uses for Neurodegenerative Diseases
10/12/2009E-255-2007/0A Target for the Development of Diagnostics and Therapeutics for Abnormal Hematopoiesis
9/2/2009E-018-2009/0Biomarkers for Sjögren's Syndrome
8/11/2009E-207-2009/0Superior Method of Preparing Dendrimers for Use as Magnetic Resonance Imaging (MRI) Contrast Agents
5/29/2009E-009-2008/0New Insect SF-9ET Cell Line for Determining Baculovirus Titers
5/28/2009E-219-2008/0Method for the Diagnosis and Prognosis of Age-Related Cardiovascular Disorders
5/5/2009E-084-2009/0Genetic Mutations Associated with Stuttering
5/5/2009E-227-2008/0Method of Detecting and Quantifying Contaminants in Heparin Preparations
5/4/2009E-223-2006/1
E-284-2008/0
Small-Molecule TSH Receptor Modulators for Diagnosis and Treatment of Thyroid Disease and Cancer
5/4/2009E-186-2008/0Identification of Subjects Likely to Benefit from Copper Treatment
3/23/2009E-219-2007/0
E-219-2007/2
Dendrimer Conjugates Targeting Adenosine Receptors, P2Y Receptors and Other Receptors of the GPCR Superfamily, for Use in the Treatment of Various Disorders, Including Neurodegenerative Diseases, Stroke, Epilepsy, Pain and Thrombosis
1/5/2009E-295-2008/0Novel Inhibitor of NF-kappa B Pathway
12/1/2008E-228-2002/0Methods and Compositions for Selectively Enriching Microbes
11/1/2008E-256-1999/0Methods for Accurately Measuring and Regulating Bound Adrenomedullin
9/1/2008E-021-2007/0Automated Method for Rapid Detection of Sickle Cell Disease Inhibitors
8/1/2008E-140-2008/0Species-Independent A3 Adenosine Receptor Agonists
7/1/2008E-229-2006/0Novel O-GLcNAcase Inhibitor and Fluorogenic Substrate as a Tool for Diagnosing Type 2 Diabetes
7/1/2008E-181-1997/06,479,286Methods and Compositions for Making Dendritic Cells from Expanded Populations of Monocytes and for Activating T Cells
7/1/2008E-075-2008/0Cripto-1 Represents a Biomarker for Chronic Inflammatory Diseases
7/1/2008E-049-2008/0Cripto-1 as a Biomarker for Cardiac Ischemia
7/1/2008E-071-2003/07,316,903Rapid and Sensitive Detection of Nucleic Acid Sequence Variations
6/1/2008E-317-2007/0Novel Fluorinated Dmt-Tic Analogues for Use as PET Radiotracers
5/1/2008E-120-2003/27,378,276Method of Inducing Memory B Cell Development and Terminal Differentiation
5/1/2008E-056-2007/0Microarray Binding Sensors Using Carbon Nanotube Transistors
5/1/2008E-298-2006/0Segmenting Colon Wall Via Level Set Techniques
2/1/2008E-114-2004/07,572,771Multi-Domain Amphipathic Helical Peptides and Methods of Their Use
7/1/2007E-149-2005/0Methods and Materials for Identifying Polymorphic Variants, Diagnosing Susceptibilities, and Treating Disease
6/1/2007E-088-2007/0Zscan4: A Gene Critical for Early Embryonic Development
5/1/2007E-168-2001/0
E-168-2001/1
7,192,705TMC1, a Deafness-Related Gene
4/1/2007E-239-2005/0Method for Promoting Stem Cell Proliferation and Survival
4/1/2007E-014-2002/0Neural Crest-Melanocyte cDNA Based Microarray Analysis for Human Skin Pigmentation Research
3/1/2007E-312-2006/0Latrophilin 3, a Gene Involved in Attention Deficit Hyperactivity Disorder
3/1/2007E-015-1993/05,516,911Fluorescent Intracellular Calcium Indicators
3/1/2007E-239-2000/0
E-239-2000/1
7,189,812
7,217,811
7,432,067
7,531,635
A Fertility Test to Detect Ovarian Autoimmune Disease Using Human Recombinant MATER Protein
2/1/2007E-317-2004/1Metal Chelators and Target-Moiety Complexes for Imaging
1/1/2007E-190-2003/0Protein Arginine N-methyltransferase 2 (PRMT-2), a Modulator of NF-kappaB, E2F1, and STAT3 Activity
1/1/2007E-163-2002/2Diagnostics and Therapeutics for Hydrocephalus
12/1/2006E-046-2006/0Small Molecules for Imaging Protein-Protein Interactions
9/1/2006E-262-2003/0Methods for Enhancing Beta Cell Function in Diabetes
8/1/2006E-042-2006/0Complement Regulatory Gene Variants as Predictive Tests for Age-related Macular Degeneration (AMD)
6/1/2006E-156-2006/0Beta-Amyloid PET Imaging Agents
5/1/2006E-030-2005/0
E-030-2005/1
Development of Gene Chip Technology for Vascular Risk Assessment
5/1/2006E-057-2005/0Novel Glycated Peptides and Proteins as Biomarkers for Diabetes Control
4/1/2006E-194-2005/0The Medusa™ Sequencer: A Sequencing Machine the Size of a Molecule that Could Sequence RNA in a Living Cell
4/1/2006E-195-2005/0Nanoprobes for Detection or Modification of Molecules
3/1/2006E-207-2005/0Measuring Fifteen Endogenous Estrogens Simultaneously in Human Urine by High-Performance Liquid Chromatography-Mass Spectrometry
3/1/2006E-263-2003/0Immunogenic T Cell Targets in Autoimmune Hepatitis and Methods of Use
2/1/2006E-122-1997/06,426,198
7,045,675
Genes For Niemann-Pick Type C Disease
12/1/2005E-258-1994/0Restenosis/Atherosclerosis Diagnosis, Prophylaxis, and Therapy
8/1/2005E-092-2004/0Anti-Marinobufagenin Antibodies and Methods for Their Use
8/1/2005E-170-2004/07,300,940Integrin Alpha-V Beta-3 Antagonists for use in Imaging and Therapy
6/1/2005E-055-2005/0
E-055-2005/1
E-055-2005/2
Farnesyltransferase Inhibitors for Treatment of Laminopathies, Cellular Aging and Atherosclerosis
6/1/2005E-354-2004/1Proteomic Profiles Associated with Aging
3/1/2005E-005-2004/0Methods for the Selection of Subjects for Multiple Sclerosis Therapy
3/1/2005E-354-2004/0Biomarkers for Osteoarthritis
3/1/2005E-010-2004/2Modulating P38 Kinase Activity
1/1/2005E-244-2004/0The UBE2G2 Binding Domain in the Ubiquitin Ligase GP78 and Methods of Use Thereof
12/1/2004E-276-2004/0Methods for Diagnosis of Atherosclerosis
10/1/2004E-306-2003/0Genetic Fingerprint of Acute Stroke
10/1/2004E-090-1999/0Simultaneous HDL/LDL/Total Lipoprotein Single Tube Homogeneous Assay
9/1/2004E-289-1988/25,209,920Evaluative Means For Detecting Inflammatory Reactivity
12/1/2003E-185-2002/0Particles for Imaging Cells
12/1/2003E-167-2003/0Method for Analysis of Biomarkers Concentrated with Biomarker Attractants
12/1/2003E-109-2000/0Pain Control by the Selective Local Ablation of Nociceptive Neurons
6/1/2003E-118-2003/0Mouse Monoclonal Antibodies Against Human IKKgamma/NEMO Protein
4/1/2003E-037-2003/0
E-037-2003/1
E-125-2003/0
Method for the Diagnosis and Treatment of Vascular Disease
3/1/2003E-185-1997/26,368,828Attenuated and Dominant Negative Variant cDNAs of STAT6: STAT6b and STAT6c
11/1/2002E-353-2001/0
E-353-2001/1
E-353-2001/2
7,229,963Methods of Inducing Deacetylase Inhibitors to Promote Cell Differentiation and Regeneration
11/1/2002E-279-2001/0FcepsilonRI -Bearing Human Mast Cell Lines
8/1/2002E-321-2001/07,109,245Methods and Compositions for Antagonizing Septic Shock
5/1/2002E-151-2001/0Method of Promoting Engraftment of a Donor Transplant in a Recipient Host
4/1/2002E-051-2002/1Methods for Using Modulators of Extracellular Adenosine or an Adenosine Receptor to Enhance Immune Response and Inflammation
2/1/2002E-067-2000/06,706,528Fluorescent Magnesium Indicators
1/1/2002E-064-2001/06,951,761Parallel Measurements of Multiple Macromolecules Using a Cryoarray
4/1/2001E-149-2000/06,756,215Biologically Active FLAG-Epitope-Tagged Transforming Growth Factor Beta (TGF-beta) Protein
12/1/2000E-185-2000/0Dombrock Blood Typing
12/1/2000E-054-2000/0Use and Targeting of CD98 Light-Chain Proteins in Therapies for Thyroid Hormone Disorders
12/1/2000E-123-1999/07,122,624PTH2 and PTH1 Receptor Ligands
7/1/2000E-070-2008/0Metabolic Biomarkers Indicate Exposure to Gamma Radiation
4/1/2000E-257-1999/0Methods and Compositions for Correlating CCR5 Expression with Essential Hypertension
8/1/1999E-045-1994/0
E-045-1994/1
5,587,309
5,888,705
Methods of Stimulating Proliferation and Differentiation of Human Pancreatic Cells Ex Vivo
7/1/1999E-077-1999/06,623,960
7,524,939
Monoclonal Antibodies Specific And Inhibitory To Human Cytochrome P450 2C8, 2C9, 2C18 And 2C19 - New Avenues For Drug Discovery
6/1/1999E-282-1998/0Antagonists of the Alpha Epsilon Beta 7 Integrin as Therapeutic Agents for Inflammatory Diseases
4/1/1999E-157-1994/16,787,306
7,402,387
Method and Composition for Detecting Dihydropyrimidine Dehydrogenase Splicing Mutations
11/1/1998E-181-1998/06,867,017A Mitochondrial-Specific ATP-Binding Transporter Gene (ABC7) Is An Iron Transporter In An Inherited Ataxia-Anemia Syndrome
10/1/1998E-009-1996/06,365,712
6,846,911
Methods And Compositions For Inhibiting Inflammation And Angiogenesis
9/1/1998E-063-1996/06,289,753Method for Measuring Mechanical Properties of the Collagen Network in Cartilage
11/1/1997E-156-1996/06,322,981Rapid Method For Diagnosing The Various Forms Of Alpha-Thalassemia
11/1/1997E-257-1997/06,627,745Identification Of The Gene Causing Familial Mediterranean Fever
5/1/1997E-046-1997/06,060,253Agents That Bind To And Inhibit Human Cytochrome P450 2D6
12/1/1996E-184-1995/0
E-184-1995/1
Materials And Methods For Detection And Treatment Of Insulin Dependent Diabetes
11/1/1996E-185-1995/05,939,530Inhibitory And Non-Inhibitory Antigen Binding Polypeptides Against Human P450 Enzymes
7/1/1996E-083-1990/05,219,991
5,527,685
Macrophage Stimulating Protein
7/1/1996E-097-1995/05,853,697Methods Of Treating Established Colitis Using Antibodies Against IL-12
7/1/1996E-141-1994/0Chromatographic Method And Device For Preparing Blood Serum For Compatibility Testing
7/1/1996E-002-1986/05,352,77275 Kilodalton Interleukin-2 Receptor Proteins And Their Use
11/1/1993E-079-1993/0
E-079-1993/1
5,518,880
5,912,173
Methods for Diagnoses and Treatment of XSCID
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