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Infectious Diseases - Therapeutics:

DateRef. No.Patent No.Title
11/10/2009E-202-2008/0A Novel Treatment for Malarial Infections
11/4/2009E-331-2007/2Viral Inactivation Using Crosslinkers and Detergents
11/4/2009E-273-2009/0Simpler is Better: The Production of Young Cell Cultures from Tumor Infiltrating Lymphocytes (TIL) Yields More Effective Adoptive Cell Transfer (ACT) Immunotherapies
11/4/2009E-201-1998/01085908Immunotoxin Useful for Treatment of AIDS
10/29/2009E-337-2001/07,368,114A Novel Multimeric CD4 Fusion Protein for Treating HIV Infection
10/21/2009E-116-2006/1
E-306-2006/4
Influenza Vaccines, Therapeutics, and Monoclonal Antibodies
10/7/2009E-328-2001/1Use of CpG Oligodeoxynucleotides to Induce Epithelial Cell Growth
10/7/2009E-147-1999/0
E-147-1999/1
6,977,245Oligodeoxynucleotide and Its Use To Induce an Immune Response
10/7/2009E-276-2007/1Neutralization of Hepatitis C Virus (HCV)
9/28/2009E-324-2004/3In Vitro Model for Hepatitis C Virion Production
9/18/2009E-281-2006/0Bactericidal Peptides from Avian Leukocyte Ribonuclease A-2
9/3/2009E-169-2004/0
E-281-2005/0
E-318-2000/0
Rapid Diagnostic Applications of Phage
9/3/2009E-012-1999/0
E-089-1998/0
E-110-1993/0
E-178-1996/0
E-179-1996/0
E-196-1997/0
E-257-2000/0
5,688,501
7,163,818
7,332,307
Therapeutic Antibacterial Applications of Phage
9/2/2009E-159-2009/0Use of a Modified Adaptor Molecule LAT to Improve Immunotherapy for Cancer and Other Diseases
7/29/2009E-205-2008/0Novel Proteins from the Sand Fly Lutzomyia longipalpis are Potent Inhibitors of Complement Activity
7/29/2009E-204-2008/0Potent Anti-Coagulant Activity of a Novel Protein from the Sand Fly Lutzomyia longipalpis
7/29/2009E-040-2004/07,504,243High-yield Methods of Producing Biliverdin
7/14/2009E-291-2008/0Membrane Proximal Region of HIV gp41 Anchored to the Lipid Layer of a Virus-Like Particle Vaccine
7/14/2009E-249-2007/0A Unique Infectious Hepatitis C Virus Clone, Strain HC-TN (genotype 1a)
7/9/2009E-198-2006/0Anti-H5N1 Influenza Activity of the Antiviral Protein Cyanovirin
7/6/2009E-074-1999/2
E-117-1995/3
6,193,982Cyanovirins and Related Conjugates, Compositions, Nucleic Acids, Vectors, Host Cells, Methods of Production and Methods of Use for Microbicide Development
7/3/2009E-074-1999/0
E-074-1999/1
E-074-1999/2
E-074-1999/3
E-117-1995/0
E-117-1995/1
E-117-1995/3
E-198-2006/0
5,821,081
5,843,882
5,962,653
5,962,668
5,998,587
6,015,876
6,193,982
6,245,737
6,420,336
6,428,790
6,586,392
6,743,577
6,780,847
6,987,096
7,048,935
7,105,169
7,339,037
The Protein Cyanovirin Inactivates HIV and Influenza
6/1/2009E-093-2000/06,905,822
7,547,519
Method of Diagnosing Multidrug Resistant Tuberculosis
6/1/2009E-114-2009/0Axenically-Produced Coxiella burnetii and Methods for Producing Axenic Coxiella burnetii
5/28/2009E-043-2009/0T Cells Attacking Cancer: T Cell Receptors that Recognize the Tyrosinase Tumor Antigen
5/27/2009E-297-2006/0CCR5-Specific Human Monoclonal Antibodies
5/15/2009E-325-2008/0Mobilizing the Body to Fight Cancer: T Cell Receptors Specific for the Tumor Antigen Survivin
5/11/2009E-352-2003/0Immunogenic West Nile Virus-Like Particles
5/4/2009E-255-2000/07,435,801Therapeutic Methods Based on In Vivo Modulation of the Production of Interferon gamma
5/4/2009E-267-2008/0Substituted Triazine and Purine Compounds for the Treatment of Chagas Disease and African Trypanosomiasis
5/4/2009E-303-2008/0Insect Salivary Proteins as Potent Adjuvants for Enhancing Immune Responses
3/30/2009E-146-2008/1Adoptive Immunotherapy for Reestablishing HIV-specific Cytotoxic T-cell (CD8 T-cell) Function in HIV and AIDS Patients and Methods for Assessing the Reestablishment of CD8 T-cell Function
3/23/2009E-161-2008/0Anti-Hepatitis C Virus Activity of the Protein Scytovirin (SVN)
3/23/2009E-304-2008/0M2e Peptide Vaccine Against Influenza Virus
3/23/2009E-162-2008/0Treatment of Schistosomiasis Using Substituted Oxadiazole 2-Oxides
3/11/2009E-078-2000/17,521,063Compounds Used to Improve Human Immune Responses in Diseases such as Allergies, Infections, and Cancer
2/17/2009E-173-2008/0Compositions and Methods for Vaccine and Virus Production
2/2/2009E-142-2008/0Humanized Monoclonal Antibodies that Specifically Bind Japanese Encephalitis Virus (JEV) and Their Use
1/9/2009E-182-2008/0Method of Treating Pneumoconiosis with Oligodeoxynucleotides
1/9/2009E-278-2007/0Attenuated Salmonella as a Delivery System for siRNA-Based Tumor Therapy
12/1/2008E-004-2004/27,025,961Anti-Plasmodium Compositions and Methods of Use
11/1/2008E-211-2008/0Fully Human Anti-Human Monoclonal Antibody Helpful in Developing Therapies Against Autoimmune and Infectious Diseases and Cancer
11/1/2008E-250-2007/0Induced Internalization of Surface Receptors
10/1/2008E-301-2003/0A Method with Increased Yield for Production of Polysaccharide-Protein Conjugate Vaccines Using Hydrazide Chemistry
10/1/2008E-204-2007/0Methods of Glycosylation and Bioconjugation
10/1/2008E-145-2004/3Monoclonal Antibodies Against Orthopoxviruses
10/1/2008E-159-2007/3Monoclonal Antibodies Against Dengue and Other Viruses With Deletion in Fc Region
10/1/2008E-279-2007/0Alpha 1-3 N-Acetylgalactosaminyltransferases with Altered Donor and Acceptor Specificities, Compositions, and Methods of Use
10/1/2008E-280-2007/0Beta 1,4-Galactosyltransferases with Altered Donor and Acceptor Specificities, Compositions and Methods of Use
10/1/2008E-066-2003/5Monoclonal Antibodies That Bind or Neutralize Dengue Virus
10/1/2008E-152-2004/0Use of Suppressive Oligonucleotides to Treat Uveitis
10/1/2008E-183-2002/0Method of Treating Infectious and Inflammatory Lung Disease with Suppressive Oligonucleotides
10/1/2008E-153-2002/0Method of Treating and Preventing Infections in Immunocompromised Subjects with Immunostimulatory CpG Oligonucleotides
10/1/2008E-089-2002/17,517,531Dengue Tetravalent Vaccine Containing a Common 30 Nucleotide Deletion in the 3'-UTR of Dengue Types 1, 2, 3, and 4
10/1/2008E-230-2002/27,482,133Catalytic Domains of [beta](1,4)-galactosyltransferase I Having Altered Donor and Acceptor Specificities, Domains That Promote In Vitro Protein Folding, and Methods for Their Use
9/1/2008E-032-1993/15,762,905
6,685,942
Human Neutralizing Monoclonal Antibodies to Respiratory Syncytial Virus and Human Neutralizing Antibodies to Respiratory Syncytial Virus
9/1/2008E-149-2006/2Compositions and Methods for Increasing Recombinant Protein Yields through the Modification of Cellular Properties
9/1/2008E-123-2007/0
E-146-2004/0
Monoclonal Antibodies that Neutralize B. anthracis Protective Antigen (PA), Lethal Factor (LF) and Edema Factor (EF)
9/1/2008E-001-1996/07,488,477Neutralizing Monoclonal Antibodies to Respiratory Syncytial Virus
9/1/2008E-236-2007/3Immunogenic Peptides Against Influenza Virus
9/1/2008E-268-2002/07,261,900Recombinant Modified Bacillus anthracis Protective Antigen for Use in Vaccines
9/1/2008E-178-1999/0
E-178-1999/1
E-178-1999/2
00810119.1
10-0905450
1287152
784216
Human-Bovine Chimeric Respiratory Syncytial Virus (RSV) Vaccines
9/1/2008E-032-2008/0Use of Saccharides Cross-Reactive with Bacillus anthracis Spore Glycoprotein as a Vaccine Against Anthrax
9/1/2008E-016-2008/0Modified Sugar Substrates and Methods of Use
9/1/2008E-343-2002/0gammaPGA Conjugates for Eliciting Immune Responses Directed Against Bacillus anthracis and Other Bacilli
8/1/2008E-141-2003/0Monoclonal Antibodies to HIV-1 Vpr
8/1/2008E-159-2008/0Polyamine Compounds That Bind Tar RNA of HIV and Methods of Treating Viral Disorders
8/1/2008E-072-2008/0HIV Immunogen and Method of Making and Using Same
8/1/2008E-043-2008/0Cross-Reactive Neutralizing Human Domain Antibody Against HIV-1
7/1/2008E-095-2008/0A Prophylactic and Therapeutic for Preventing and Treating Tularemia by Rapid Activation of Host Cells and Antigen Recognition
5/1/2008E-012-2008/0C4'-Substituted-2-Deoxyadenosine Analogs and Methods of Treating HIV
5/1/2008E-206-1995/36,320,022
7,101,548
Treatment and Diagnosis of Cancer, Diabetes and other Disorders Using Adrenomedullin Peptides and Antibodies
4/1/2008E-003-2007/0Engineered Human Antibody Constant Domains (Nanoantibodies) as Scaffolds for Binders
4/1/2008E-036-2005/0Identification of a Cell-Surface Co-Receptor that Mediates the Uptake and Immunostimulatory Activity of ā€œDā€ Type CpG Oligonucleotides
3/1/2008E-316-2003/0Immunoglobulins with Potent and Broad Antiviral (HIV) Activity Based on scFv Joined by Flexible Linker to Fc
3/1/2008E-247-2002/1Modulators of Nuclear Hormone Receptor Activity: Novel Compounds, Diverse Applications for Infectious Diseases, Including Anthrax (B. anthracis)
2/1/2008E-116-2004/0Coacervate Microparticles Useful for the Sustained Release Administration of Therapeutics Agents
2/1/2008E-055-2007/3Inhibiting HIV Infection Using Integrin Antagonists
2/1/2008E-208-2007/0Eeyarestatins: Novel Deubiquitination Inhibitors for the Treatment of Drug-Resistant Cancers
11/1/2007E-076-1997/1Novel Non-Nucleoside Agents for the Inhibition of HIV Reverse Transcriptase for the Treatment of HIV-1
10/1/2007E-104-2004/0
E-104-2004/1
Method for Inducing T-Cell Proliferation
10/1/2007E-308-2005/0Discovery of Tropolone Inhibitors of HIV-1 Integrase that can be Used for the Treatment of Retroviral Infection, Including AIDS
10/1/2007E-264-2006/0Integrase Inhibitors for the Treatment of Retroviral Infection Including Human Immunodeficiency Virus-1
10/1/2007E-237-2007/0HIV-1 Integrase Inhibitors for the Treatment of Retroviral Infections
10/1/2007E-039-2002/0Potent HIV-1 Entry Inhibitors and Immunogens
10/1/2007E-187-2003/0Quinoline Inhibitors of Retroviral Integrase
9/1/2007E-137-2005/0Methods and Compositions for Treating FUS1 Related Disorders
8/1/2007E-013-2006/1Antiviral Compounds with Broad Neutralization Capabilities
8/1/2007E-179-2007/0Methods for Prevention and Treatment of Polyomavirus Infection or Reactivation (E-179-2007)
8/1/2007E-068-1998/06,685,933
7,235,232
Interferon Alpha Hybrids
7/1/2007E-151-2006/0
E-151-2006/1
Viral Entry or Replication Inhibitors
6/1/2007E-144-2004/0Monoclonal Antibodies That Bind or Neutralize Hepatitis B Virus
6/1/2007E-090-1996/07,151,087
7,374,872
CC Chemokine Receptor 5 DNA, New Animal Models and Therapeutic Agents for HIV Infection
6/1/2007E-274-2000/07,527,797Vibrio cholerae O139 Conjugate Vaccines
4/1/2007E-121-2002/07,572,828Identification of Anti-HIV Compounds Inhibiting Virus Assembly and Binding of Nucleocapsid Protein to Nucleic Acid
2/1/2007E-130-2001/07,223,844
7,378,093
Broadly Cross-Reactive Neutralizing Antibodies against Human Immunodeficiency Virus Selected by ENV-CD4-CO-Receptor Complexes
12/1/2006E-252-2001/0HIV Entry Inhibitor
11/1/2006E-200-1998/07,470,506Methods for Treating Drug-Resistant HIV-1 Infection
9/1/2006E-017-2006/0Organic Thiophosphate Antiretroviral Agents
8/1/2006E-166-2006/0A Novel Small Protein Antibiotic
8/1/2006E-180-2006/0Neutralizing Monoclonal Antibodies to Botulinum neurotoxin A
8/1/2006E-329-2000/07,528,274Novel Acylthiol Compositions and Methods of Making and Using Them
7/1/2006E-017-2004/0Methods and Compositions Related to GHS-R Antagonist
5/1/2006E-055-1999/06,680,176Identification of Candidate Ligands which Modulate Antigen Presenting Cells
5/1/2006E-265-2003/0Methods for Inhibiting HIV and Other Viral Infections by Modulating Ceramide Metabolism
5/1/2006E-114-2003/0Methods and Compositions for the Inhibition of HIV-1 Replication
2/1/2006E-072-1992/05,976,541Potent Peptide for Stimulation of Cytotoxic T Lymphocyte Specific for the HIV-1 Envelope
2/1/2006E-025-2006/0Anti-Viral Griffithsin Compounds, Compositions, and Methods of Use
2/1/2006E-152-1991/15,932,218
6,214,347
6,294,322
Multideterminant Peptides That Elicit Helper T-Lymphocyte Cytotoxic T-Lymphocyte and Neutralizing Antibody Responses Against HIV-1
2/1/2006E-174-1993/1
E-174-1993/2
0782632
6,001,555
6,989,263
The CCHC Zinc Fingers of the Retroviral Nucleocapsid Protein Comprises a New Target Useful in Identification and Evaluation of Anti-HIV Therapeutics
2/1/2006E-249-2004/1
E-308-2000/0
Therapeutic HIV Vaccine Vectors for Individuals Receiving Antiretroviral Therapy
12/1/2005E-253-2005/0Methods and Compositions for the Inhibition of SARS-CoV Replication Propagation and Transmission
12/1/2005E-142-2005/0A Single Ribozyme to Catalyze both Trimming and Transacting Catalysis - Potential Therapeutic for HPV Infection and Cervical Cancer
12/1/2005E-133-2005/0Genomic Nucleic Acid Sequence for Cyanovirin-N and Signal Peptide Thereof
11/1/2005E-104-2005/1Furin Inhibitors and Alpha-Defensin for Preventing Papilloma Virus Infection
11/1/2005E-051-2005/0Identification of a Fusion/Entry Receptor for Human Herpesvirus-8
8/1/2005E-180-2005/0Scytovirin Domain 1 (SD1) Related Polypeptide
8/1/2005E-137-2003/1Vaccines and Methods of Treating Drug-Resistant HIV-1 and Hepatitis B Viruses
8/1/2005E-155-2005/0
E-155-2005/1
E-155-2005/2
E-155-2005/3
Immunogenic Peptides From Human Papillomavirus Type 16 E2
8/1/2005E-047-2005/0North-2'-Deoxy-Methanocarbathymidines as Antiviral Agents Against Poxviruses
8/1/2005E-046-2005/0A Novel Interleukin-12 (IL-12) Inducing Protein Isolated from Toxoplasma gondii Inflammatory Profilin (TGIP)
8/1/2005E-302-2004/0A32 Monoclonal Antibody Fusion Protein for Use as HIV Inhibitors and Vaccines
8/1/2005E-257-2000/07,163,818Bacteriophage Having Multiple Host Range
8/1/2005E-318-2000/0Method for Determining Sensitivity to a Bacteriophage
6/1/2005E-043-2005/0Cell Culture System for Efficient Expression of Self-Replicating Norwalk Virus
6/1/2005E-121-2004/0A New Antiviral Pathway that is Responsible for Viral Clearance: Modulation of ADAR1 Activities Enhance Antiviral Therapies and Virus Infection of Tissue Culture Systems
6/1/2005E-050-1998/06,153,421
7,201,911
Cloned Genomes Of Infectious Hepatitis C Virus And Uses Thereof
6/1/2005E-271-2003/0
E-271-2003/1
Epitopes of Ebola Virus Glycoproteins Useful for Vaccine Development
5/1/2005E-330-2004/07,408,075Synthesis of Phosphocholine Ester Derivatives and Conjugates Thereof
5/1/2005E-355-2001/27,494,813VAC-BAC Shuttle Vector System
5/1/2005E-279-2004/0Treatment of Human Viral Infections (Resveratrol)
5/1/2005E-280-2004/0Treatment of Human Viral Infections (Proteosome Inhibitors)
5/1/2005E-281-2004/0Treatment of Human Viral Infections (Imatinib)
5/1/2005E-282-2004/0Treatment of Human Viral Infections (Farnesyl Transferase Inhibitors)
4/1/2005E-176-2003/0Antibodies Against the Amino Terminus Region of Circumsporozoite Protein Prevent the Onset of Malaria
4/1/2005E-150-2001/17,175,838Use of a Promoter of T-cell Expansion and an Inducer of CD40 Stimulation in the Treatment or Prevention of a Pathologic State
4/1/2005E-263-2002/0Peptide Inhibitors of Yersinia Phosphatase (YopH) as Potential Treatments Against Plague
4/1/2005E-023-2003/07,303,754MVA Expressing Modified HIV envelope, gag, and pol Genes
3/1/2005E-251-2004/0Broadly Cross-Reactive HIV-1 Neutralizing Human Monoclonal Antibodies
3/1/2005E-215-2004/0CpG Oligonucleotide Prodrugs
3/1/2005E-076-2004/0An Epitope-Enhancement of Human CD4 HIV Epitope
3/1/2005E-160-2002/07,541,139Tryptophan as a Functional Replacement for ADP-ribose-arginine in Recombinant Proteins
1/1/2005E-191-2003/1Eosinophil-Derived Neurotoxin, an Antimicrobial Protein with Ribonuclease Activity, is an Immunostimulant
12/1/2004E-004-2005/0
E-004-2005/4
Human Monoclonal Antibodies Against Hendra and Nipah Viruses
12/1/2004E-299-2004/0Vaccines Against Crimean-Congo Hemorrhagic Fever
11/1/2004E-233-2004/0
E-233-2004/1
Anti-HIV Peptide Secreting Bacteria: Therapeutics and Methods of Use
10/1/2004E-049-2004/07,303,751Anti-Plasmodium Compositions and Methods of Use
10/1/2004E-256-2004/0Inhibitors of HIV Ribonuclease H Antiviral Properties
10/1/2004E-272-2004/07,510,715Protozoan Derived Antagonist of CCR5
8/1/2004E-106-2003/0Griffithsin, Glycosylation-Resistant Griffithsin, and Related Conjugates, Compositions, Nucleic Acids, Vectors, Host Cells, Methods of Production and Methods of Using
6/1/2004E-228-2003/1
E-228-2003/2
Soluble SARS Coronavirus Spike Protein (S Protein)
6/1/2004E-150-2004/0A Peptide that Elicits Neutralizing Antibodies Targeting the HIV Co-Receptor CCR5
6/1/2004E-335-2003/0
E-335-2003/1
Mechanisms for Improving the Breadth of the Immune Response to Diverse Strains and Clades of HIV
4/1/2004E-073-2004/0Reduction of HIV-1 Replication by a Mutant Apolipoprotein B mRNA Editing Enzyme-Catalytic Polypeptide-like 3G (APOBEC3G)
4/1/2004E-326-2002/0
E-326-2002/2
Triplex Hairpin Ribozyme
4/1/2004E-068-2004/0MVL, an Antiviral Protein from a Cyanobacterium
3/1/2004E-008-1996/0C-C Chemokines That Inhibit Retrovirus Infection
2/1/2004E-286-2002/0
E-286-2002/1
E-286-2002/2
Aerosolized Capreomycin for Inhibition of Pulmonary Tuberculosis
1/1/2004E-324-2003/0Streptococcus Lipoprotein Antigens
1/1/2004E-189-1998/0Inhibitors of Formation of Protease Resistant Prion Protein
12/1/2003E-191-2001/0gp64 Pseudotyped Vectors and Uses Thereof
12/1/2003E-019-2004/0Construction of Replication-Competent Chimeric Simian Immunodeficiency Virus (SIV) Human Immunodeficiency Virus Type 1 (HIV-1) Viruses that Replicate Using HIV-1 Reverse Transcriptase and Integrase (IN): A Model System for Development and Testing of Antiviral Agents for the Treatment of HIV-1 Infection
12/1/2003E-276-2003/0HIV-Dependent Expression Vector
12/1/2003E-022-2003/0Discovery of Novel Inhibitors of HIV-1 Integrase and/or RNase H That Can Be Used for the Treatment of Retroviral Infection Including AIDS
11/1/2003E-090-1994/0
E-200-1994/0
E-200-1994/2
E-201-1994/0
E-201-1994/1
5,571,919
5,578,729
5,639,761
5,786,482
5,789,594
6,627,641
Novel Antimalarial Compounds, Methods of Synthesis Thereof, Pharmaceutical Compositions Comprising Same, and Methods of Using Same for Treatment and Prevention of Malaria
11/1/2003E-086-1999/06,875,855
7,332,167
Molecular Diagnosis of Disseminated Candida albicans Infection Using Hemoglobin-Response Gene
11/1/2003E-145-1987/0
E-145-1987/1
E-145-1987/2
E-217-1988/0
5,221,732
5,567,681
5,643,876
Antimicrobial Magainin Peptides
11/1/2003E-072-2001/07,119,193Identification of New Small RNAs and ORFs
11/1/2003E-224-2003/0Inhibition of Retrovirus Gene Expression by PSF
11/1/2003E-285-2002/07,485,306Lutozmyia longipalpis Polypeptides and Methods of Use
9/1/2003E-150-1994/05,622,861Hepatitis A Virus Receptor And Methods Of Use
9/1/2003E-145-2002/0Sigma-2 Receptor Agonists Inhibit HIV Infection and Replication in Lymphocytes
9/1/2003E-224-2002/0Novel Anti-Tumor and Anti-Fungal Compounds Isolated from Plants of the Genus Aniba
8/1/2003E-225-2003/0Protection Against Vertical Transmission of Pathogenic Infections
8/1/2003E-327-2002/0Inhibition of HIV-1 Replication by the Ribonuclease, Recombinant Angiogenin
8/1/2003E-063-2003/0Rapamycin Resistant T Cells and Therapeutic Uses Thereof
7/1/2003E-190-2000/0Methods and Compositions for Inhibiting HIV-Coreceptor Interactions
7/1/2003E-173-2001/0HTLV-1 p30II and p12I Proteins as Therapeutic Targets in HTLV-1 Infected Individuals
5/1/2003E-097-2003/0Triggering Receptors Expressed in Myeloid Cells (TREM) Like Transcript (TLT-1), A Novel Inhibitory Receptor of Platelets and Uses Therefore
5/1/2003E-240-2002/0HTLV-1 Cell Binding and Inhibition
4/1/2003E-017-2002/07,491,798Scytovirins and Related Conjugates, Antibodies, Compositions, Nucleic Acids, Vectors, Host Cells, Methods of Production and Methods of Using Scytovirin
2/1/2003E-008-2003/0Scavenger Receptor BI Targeting for the Treatment of Infection, Sepsis and Inflammation
1/1/2003E-144-2002/0
E-144-2002/1
7,566,451vel Broadly Cross-Reactive HIV Neutralizing Human Monoclonal Antibodies Selected from Fab Phage Display Libraries Using a Novel Strategy Based on Alternative Antigen Panning
and
Novel Broadly Cross-Reactive HIV-1 Neutralizing Human Single-Chain Antibodies Derived from X5 by DNA Shuffling and Alternating Antigen Panning
12/1/2002E-090-2002/0Assays for Assembly of Ebola Virus Pseudoparticles Relevant to Antiviral Therapy and Vaccines
11/1/2002E-317-2001/0Discovery of Novel Inhibitors of HIV-1 Integrase That Can Be Used for the Treatment of Retroviral Infection Including AIDS
11/1/2002E-080-2002/07,511,015Modified Defensins and Their Use
10/1/2002E-356-2001/07,282,205Four Chimpanzee Monoclonal Antibodies that Neutralize Hepatitis A Virus
8/1/2002E-096-2002/07,276,227An Obligate Domain-Swapped Dimer of Cyanovirin with Enhanced Anti-Viral Activity
8/1/2002E-321-2001/07,109,245Methods and Compositions for Antagonizing Septic Shock
4/1/2002E-099-2001/0Mitochondrial Topoisomerase I
3/1/2002E-328-2001/07,615,227Use of CpG Oligodeoxynucleotides to Encourage Angiogenesis
2/1/2002E-282-2001/0N-Formyl Peptide Receptor Mediation of Platelet Chemotaxis Toward Injured Cells and Activation of Immune Response
2/1/2002E-214-2001/07,354,909Novel Method for Rapidly Generating Mature Dendritic Cells from Peripheral Blood Monocytes and Myeloid Precursors
2/1/2002E-215-2001/0Use of Sterically Stabilized Cationic Liposomes to Efficiently Deliver CpG Oligonucleotides in vivo
2/1/2002E-218-2001/07,514,414Identification of DNA Sequence Motifs that Suppress the Immune Response to CpG DNA
2/1/2002E-122-2001/07,388,089Anti-Arthropod Vector Vaccines, Methods of Selecting, and Uses Thereof
2/1/2002E-242-2001/0Strategies to Destabilize the Active HIV-1 Protease Dimer Resulting in Stable Monomer Formation
1/1/2002E-126-2000/06,673,905
7,211,445
A Method for Bioconjugation Using Diels-Alder Cycloaddition
1/1/2002E-285-2000/0LL-37 is an Immunostimulant
1/1/2002E-089-2001/0Suppression of CCR5- but not CXCR4-Tropic HIV-1 Replication in Lymphoid Tissue by Human Herpes Virus 6
1/1/2002E-126-2001/07,189,513
7,507,538
Human Papilloma Virus Immunoreactive Peptides
11/1/2001E-051-1990/0
E-081-1987/1
5,376,642Method of Treating HIV with 2',3'-Dideoxyinosine (ddI; didanosine)
9/1/2001E-179-2001/0Identification of a Cell-surface Receptor for Papillomaviruses
6/1/2001E-249-2000/07,009,0505-Substituted Derivatives of Conformationally Locked Nucleoside Analogues
4/1/2001E-188-2000/0Method of Preparing a Production Intermediate for HIV Protease Inhibitors
4/1/2001E-276-2000/0A Method of Inhibiting Viral Replication Targeting the Nucleocapsid Protein
2/1/2001E-082-1996/0Simian-Human HAV Chimeras Encoding a Hepatitis A Virus Having a Chimeric 2C Protein
12/1/2000E-208-2000/07,078,508Ixodes scapularis Tissue Factor Pathway Inhibitor
12/1/2000E-207-2000/07,153,947Ixodes Salivary Anticomplement Protein
9/1/2000E-061-1999/0Polypeptides Comprising IL-6 Ligand Binding Receptor Domains and Related Nucleic Acids, Antibodies, Compositions and Methods
7/1/2000E-245-1999/07,304,127Polypeptides that Bind HIV gp120 and Related Nucleic Acids, Antibodies, Compositions, and Methods of Use
7/1/2000E-068-2000/0Molecules That Influence Pathogen Resistance
4/1/2000E-203-1999/06,855,323Identification of the Domain of Plasmodium falciparum Erythrocyte Membrane Protein (PfEMP1) that Mediates Adhesion to Chondroitin Sulfate A
10/1/1999E-210-1998/06,613,764
7,132,420
Aspartic Protease Inhibitors, Compositions, and Associated Therapeutic Methods
10/1/1999E-220-1994/05,728,718
5,925,780
6,066,656
2,5-diamino-3,4-disubstituted-1,6-diphenylhexane Isosteres Comprising Benzamide, Sulfonamide and Anthranilamide Subunits and Methods of Using
9/1/1999E-107-1996/06,316,190Oligonucleotides Which Specifically Bind Retroviral Nucleocapsid Proteins
9/1/1999E-216-1994/06,057,346Inhibition of Retroviral LTR Promoters by Calcium Response Modifiers
9/1/1999E-059-1996/06,686,333Inhibition of HIV Replication Using Soluble Tat Peptide Analogs
6/1/1999E-092-1988/0Immunologically Active Peptides From The HIV Envelope Protein Eliciting Both Antibody And T Cell Responses
4/1/1999E-138-1995/05,872,210Transframe Peptide Inhibitor Of Viral Protease
2/1/1999E-217-1998/06,719,978
7,371,572
7,479,280
Chimeric Virus-Like Particles For The Induction Of Autoantibodies
1/1/1999E-099-1990/05,474,935Adeno-Associated Virus (AAV)-Based Eucaryotic Vectors
10/1/1998E-099-1991/15,455,251
5,654,432
Michellamine Antiviral Agents, Compositions, And Treatment Methods
10/1/1998E-090-1994/05,639,761
6,627,641
Antimalarial Napthylisoquinoline Alkaloids And Pharmaceutical Compositions And Medicinal Uses Thereof
10/1/1998E-096-1994/05,409,938Antimalarial Korupensamines And Pharmaceutical Compositions And Medical Uses Thereof
10/1/1998E-201-1994/05,571,919
5,789,594
Dimeric Naphthylisoquinoline Alkaloids And Synthesis Methods Thereof
10/1/1998E-200-1994/0Monomeric Naphthylisoquinoline Alkaloids And Synthesis Methods Thereof
10/1/1998E-201-1994/15,578,729
5,786,482
Dimeric Arylisoquinoline Alkaloids And Synthesis Methods Thereof
10/1/1998E-200-1994/2Monomeric And Dimeric Arylisoquinoline Alkaloids And Derivatives Thereof
9/1/1998E-039-1996/06,046,228Anti-Viral Pharmaceutical Compositions Containing 1,2-Dithiane Compounds And Methods Of Using Thereof
9/1/1998E-290-1997/07,105,488G-Protein Coupled Receptor Antagonists
5/1/1998E-202-1997/0Methods For Treating Parasitic Infection Using Thiopeptides
3/1/1998E-209-1997/06,600,030Delayed Progression To AIDS By A Missense Allele Of The CCR2 Gene
3/1/1998E-222-1997/0Functional Promoter For CCR5
3/1/1998E-230-1997/0Human Papilloma Virus Inhibition By Antisense Oligonucleotides
3/1/1998E-087-1997/0STRL33, A Human Fusion Accessory Factor Associated With HIV Infection
10/1/1997E-120-1993/0Diagnostic Reagents And Vaccines For Multiple Genotypes Of Hepatitis C Virus
5/1/1997E-019-1993/05,449,608Parvovirus B19 Receptor And Parvovirus B19 Detection
11/1/1996E-017-1996/16,197,578Cells Expressing Both Human CD4 And A Human Fusion Accessory Factor Associated With HIV Infection
10/1/1996E-061-1992/05,317,009Anti-HIV Proteins GAP 31, DAP 30 And DAP 32 And Therapeutic Uses Thereof
10/1/1996E-190-1990/05,484,889Plant Protein Useful For Treating Tumors And HIV Infection
10/1/1996E-085-1992/05,532,214An Anti-HIV Protein, TAP 29, From Trichosanthes, DNA Coding Therefor And Therapeutic Uses Thereof
8/1/1996E-226-1993/05,677,275
5,877,148
Treatment Of Cancer With Human Chorionic Gonadotropin
8/1/1996E-029-1996/05,763,464Novel Retroviral Agents Containing Anthranilamide, Substituted Benzamide And Other Subunits, And Methods Of Using Same
4/1/1996E-209-1993/05,439,899Cosalane And Related Compounds Having Activity Against AIDS And AIDS-Related Infections
4/1/1996E-169-1993/05,990,088Method For Treatment Of Kaposi's Sarcoma (KS) By Antisense Oligonucleotides
2/1/1996E-038-1995/05,681,832Amido Substituted Stilbenes And Related Compounds With In Vitro Anti-HIV Activity
5/1/1995E-134-1994/0Hepatitis C Virus Core Peptide For Stimulation Of Cytotoxic T Lymphocytes
11/1/1994E-325-1983/25,516,630Production Of Complementary DNA Representing Hepatitis A Viral Sequences By Recombinant DNA Methods And Uses Therefor
11/1/1994E-023-1994/05,498,719Diastereoselective Process Leading To A Key Intermediate For The Preparation Of Fluorinated Reverse Transcriptase Inhibitors
11/1/1994E-095-1994/05,610,198Novel Anti-Mycobacterial Compositions and Their Use for the Treatment of Tuberculosis and Related Diseases
11/1/1994E-037-1993/05,386,021
5,514,600
Mammalian Guanine Nucleotide-Binding Protein with an ADP-Ribosylation Factor Domain (ARD1)
11/1/1994E-076-1992/0Clones Encoding Mammalian ADP-Ribosylarginine Hydrolases
1/1/1991E-493-1985/0
E-493-1985/1
3-Deazaneplanocin, Intermediates for It, and Antiviral Composition and Method of Treatment Using It
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