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Central Nervous System - Therapeutics:

DateRef. No.Patent No.Title
11/4/2009E-158-2003/1New Derivative of Dextromethorphan for Use in Neuronal Therapy
7/29/2009E-040-2004/07,504,243High-yield Methods of Producing Biliverdin
7/9/2009E-128-2006/0Novel Dopamine Receptor Ligands as Therapeutics for Central Nervous System Disorders
7/2/2009E-127-1995/0
E-127-1995/1
E-127-1995/2
E-138-1994/0
E-196-2004/0
6,884,871
6,924,367
7,049,291
7,148,036
7,220,558
7,563,596
Novel Osteobiologic Proteins for Treatment of Osteoporosis, Rheumatoid and Neurologic Diseases
7/2/2009E-127-1995/0
E-127-1995/1
E-127-1995/2
6,884,871
6,924,367
7,049,291
7,563,596
Isolation And Use Of Tissue Growth-Inducing FRZB Protein
11/1/2008E-187-2007/0Indoline Compounds for the Treatment of Spinal Muscular Atrophy (SMA) and Other Diseases
9/1/2008E-216-2007/0Use of Razoxane for the Treatment of Alzheimer's Disease
9/1/2008E-153-2005/2Prevention and Treatment of Multiple Sclerosis (MS) by Administering E-Selectin
8/1/2008E-182-2007/0Methods for Promoting Stem Cell Proliferation and Survival
8/1/2008E-101-2004/0Treatment of Alcoholism by Inhibition of the Neuropeptide Y Receptor
7/1/2008E-211-2006/0Therapeutic Application of Fatty Acid Amide Hydrolase Inhibitors
6/1/2008E-245-2006/0Novel Isoform of KCNH2 for the Treatment of Schizophrenia
5/1/2008E-206-1995/36,320,022
7,101,548
Treatment and Diagnosis of Cancer, Diabetes and other Disorders Using Adrenomedullin Peptides and Antibodies
2/1/2008E-203-2000/07,144,918Biologically Active Macrolides, Compositions and Uses Thereof
1/1/2008E-153-2007/0Nitroxide Radical as a Treatment for Neurodegeneration
7/1/2007E-059-2006/0Method of Treating or Preventing Oxidative Stress-related Diseases (stroke and neurodegenerative diseases, wound healing and cardiovascular diseases)
5/1/2007E-133-2006/1New Compounds and Methods for the Treatment of Spinal Muscular Atrophy and Other Diseases
4/1/2007E-239-2005/0Method for Promoting Stem Cell Proliferation and Survival
4/1/2007E-103-2000/0
E-103-2000/1
E-103-2000/2
E-305-2005/0
6,753,317
6,916,905
Novel Dmt-Tic Analogues Specific for Delta- and Mu-Opioid Receptors
12/1/2006E-295-2005/0Novel Treatments for Autoimmune Neuroinflammatory Diseases including Multiple Sclerosis
9/1/2006E-271-2005/0Novel Treatment of Vascular Cognitive Impairment
8/1/2006E-336-2001/0Amyloid Beta is a Ligand for FPR Class Receptors
5/1/2006E-305-2005/0Potent Pharmacophoric Delta- and Mu-Opioid Receptor Antagonists and Conversion of Endomorphin Mu-Opioid Agonists to Antagonists
5/1/2006E-075-2003/0Use of Cripto-1 as a Biomarker for Neurodegenerative Disease and Method of Inhibiting Progression Thereof
3/1/2006E-262-1999/17,459,536Monoclonal Antibodies Which Specifically Bind to the Ligand Hepatocyte Growth Factor (HGF) and are Useful in the Treatment of Cancer
2/1/2006E-175-2004/0Rapid Anti-Depressant Response Produced by Low Dose Treatment with Anti-Muscarinic Drugs
1/1/2005E-130-2004/0Novel Methods for Reducing Inflammation and Treating Diseases such as Parkinson’s and Alzheimer’s Disease
12/1/2004E-071-2000/06,468,524AAV4 Vector and Uses Thereof
12/1/2004E-072-2000/06,855,314AAV5 Vector for Transducing Brain Cells and Lung Cells
6/1/2004E-035-2004/0
E-035-2004/1
E-035-2004/2
E-035-2004/3
Stem Cell Factor (SCF) Stimulates Neural Stem Cell Migration to Sites of Brain and Spinal Cord Injury
2/1/2004E-091-2003/0Methods for the Treatment of Parkinson's Disease and Other alpha-synucleinopathies
12/1/2003E-109-2000/0Pain Control by the Selective Local Ablation of Nociceptive Neurons
7/1/2003E-251-2002/0
E-251-2002/1
Structurally Rigid Dopamine D3 Receptor Selective Ligands as Cocaine and Methamphetamine Abuse Therapeutics
8/1/2002E-247-2001/0Methods of Diagnosing and Treating Schizophrenia
5/1/2002E-206-2000/0
E-206-2000/1
Enhanced Distribution of Therapeutic Agents After Local Delivery
4/1/2002E-174-2000/0Effect of COMT Genotype on Frontal Lobe Function
12/1/2001E-209-2001/0
E-209-2001/1
E-209-2001/2
7,427,590Neurotrophic Components of the ADNF I Complex
12/1/2001E-209-2001/0Neurotrophic Components of the ADNF I Complex
9/1/2001E-141-2000/07,153,882Agents Useful for Reducing Amyloid Precursor Protein and Treating Dementia and Methods of Use Thereof
5/1/2001E-203-1994/05,693,779Production and Use of Anti-Dorsalizing Morphogenetic Protein
5/1/2001E-222-2000/0Novel Inhibitors of p53 for Treatment of Neurodegenerative Disorders, Myocardial Infarction and Other Tissue Insults
12/1/2000E-123-1999/07,122,624PTH2 and PTH1 Receptor Ligands
8/1/2000E-041-2000/06,448,245HIV Protease Inhibitors, Ritonavir and Saquinavir are Potent Inhibitors of Calcium Activated Neutral Peptidases, Calpains
5/1/2000E-301-1999/06,881,718Novel Disulfide Conjugated Cell Toxins and Methods of Making and Using Them
6/1/1999E-044-1998/06,596,269Virally Mediated Gene Therapy For The Control Of Chronic Or Persistent Pain
3/1/1999E-023-1996/0
E-023-1996/1
E-023-1996/2
6,316,423Method of Treating Ischemic, Hypoxic, and Anoxic Brain Damage
2/1/1999E-235-1998/06,787,356Cell Expansion System For Use In Neural Transplantation
10/1/1998E-218-1997/06,068,844The Application Of Induction Tolerance By Oral Feeding Of Myelin Basic Protein To The Generation Of Increased Resistance To Stroke
10/1/1998E-287-1997/0
E-287-1997/1
E-287-1997/2
6,630,507Cannabinoids As Neuroprotectants
5/1/1997E-152-1996/06,387,389Sustained-Release Derivatives of Hydroxylated Analogs of Substituted 1- [2[bis(aryl)methoxy]-ethyl] -Piperazines and -Homopiperazines and Their Use as Noncompetitive Antagonists of Dopamine Reuptake Inhibitors
1/1/1997E-050-1996/06,156,7652,2'-Bipyridyl, a Ferrous Chelator, Prevents Vasospasm in a Primate Model of Subarachnoid Hemorrhage
1/1/1997E-132-1996/06,780,413Immunotoxin (MAB-RICIN) For The Treatment Of Focal Movement Disorders
12/1/1996E-078-1995/15,792,7754'- And 4',4"-Substituted-3alpha(diphenylmethoxy)tropane Analogs As Cocaine Therapeutics
3/1/1996E-171-1994/05,780,589Application of Highly Potent and Ultraselective delta Opioidmimetic Peptide Antagonists for Biochemical, Pharmacological, Clinical and Therapeutic Studies
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