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Cancer - Therapeutics:

DateRef. No.Patent No.Title
11/10/2009E-192-2008/1Optimized Expression of IL-12 Cytokine Family
11/4/2009E-273-2009/0Simpler is Better: The Production of Young Cell Cultures from Tumor Infiltrating Lymphocytes (TIL) Yields More Effective Adoptive Cell Transfer (ACT) Immunotherapies
11/4/2009E-205-2009/0Treating Cancer with Anti-Angiogenic Chimeric Antigen Receptors
11/4/2009E-275-2002/1Adoptive T-Cell Transfer After Lymphodepletion Promotes Tumor Regression
11/3/2009E-083-2002/2Use of Discoidin Domain Receptor 1 (DDR1) and Agents that Affect the DDR1/Collagen Pathway
10/28/2009E-296-2009/0Novel Inhibitors of Interleukin-6 for Kaposi Sarcoma Therapy
10/27/2009E-295-2009/0Prediction of Immune Response Outcomes to Keyhole Limpet Hemocyanin (KLH) Treatment
10/12/2009E-163-2009/0B-cell Surface Reactive Antibodies for the Treatment of B-Cell Chronic Lymphocytic Leukemia
10/10/2009E-211-2005/0Sensitizing Cancer Cells to DNA Targeted Therapies
10/7/2009E-268-2007/0A Fold-Back Diabody Format for Diphtheria Toxin-Based Immunotoxins That Can Increase Binding and Potency
9/23/2009E-027-2005/0Novel Chemoattractant-Based Toxins to Improve Vaccine Immune Responses for Cancer and Infectious Diseases
9/23/2009E-110-2004/07,504,430Novel Agents Exhibiting Cytotoxicity Against Human Tumor Cell Lines
9/9/2009E-089-2009/0Immunogenic Tumor-associated Antigen SPANX-B for Selective Cancer Immunotherapy
9/2/2009E-159-2009/0Use of a Modified Adaptor Molecule LAT to Improve Immunotherapy for Cancer and Other Diseases
8/14/2009E-063-2008/1Nanoparticles for Imaging and Treatment of Brain Tumors
7/29/2009E-157-2009/0Treatment of Cancer Using Metal Coordinating Compounds that Kill Multi-Drug Resistant Cancer Cells
7/29/2009E-250-2005/0Methods for Treating or Ameliorating Fibrosis by Inhibiting the Interaction between IL-21 Receptor (IL-21R) and IL-21
7/29/2009E-040-2004/07,504,243High-yield Methods of Producing Biliverdin
7/2/2009E-017-2008/0Novel Compounds that Specifically Kill Multi-Drug Resistant Cancer Cells
7/2/2009E-127-1995/0
E-127-1995/1
E-127-1995/2
E-138-1994/0
E-196-2004/0
6,884,871
6,924,367
7,049,291
7,148,036
7,220,558
7,563,596
Novel Osteobiologic Proteins for Treatment of Osteoporosis, Rheumatoid and Neurologic Diseases
7/2/2009E-042-2009/0Immunogenic Peptide from NGEP Protein for Developing Prostate Cancer Vaccines
7/2/2009E-033-2008/0Therapeutic Applications of a p53 Isoform in Regenerative Medicine, Aging, and Cancer
7/2/2009E-137-2002/0Methods for Treating Cancer in Humans Using IL-21
6/30/2009E-243-2002/1Recombinant Vaccinia Viruses Expressing IL-15 and Methods of Using the Same
6/23/2009E-181-2009/0New Inhibitors of Polo-like Kinase 1 (PLK1) as Anti-Cancer Agents
6/23/2009E-170-2009/0Increasing the Effectiveness of Cancer Treatment: T Cell Receptors Designed to Release Interleukin-12 Specifically at Cancer Sites
6/11/2009E-164-2007/0Compounds Binding to the N-Terminal Domains of STAT Proteins as Therapeutic Agents
5/28/2009E-148-2009/0Novel Method of Treating Cancer Using Ixolaris
5/28/2009E-340-2008/0Methods for Identifying Breast Cancer Patients for Therapy with mTOR Inhibitors
5/28/2009E-043-2009/0T Cells Attacking Cancer: T Cell Receptors that Recognize the Tyrosinase Tumor Antigen
5/28/2009E-312-2007/1New Weapons to Attack Cancer: T Cell Receptors Designed to Recognize Tumors with Enhanced Affinity
5/15/2009E-325-2008/0Mobilizing the Body to Fight Cancer: T Cell Receptors Specific for the Tumor Antigen Survivin
5/15/2009E-025-1998/06,610,684Fused Azepinone Cyclin Dependent Kinase Inhibitors
5/11/2009E-304-2006/0Enhanced Function of Gene Modified T-Cells: Identification of T-Cell Receptors (TCR) with Altered Amino Acid Sequence
5/5/2009E-326-2008/0Small Molecule Activators of Human Pyruvate Kinase for Treatment of Cancer and Enzyme-Deficient Hemolytic Anemia
5/5/2009E-179-2008/0Salcut-NH2: A Novel Target for Development of Anti-Tumorigenic, Anti-Angiogenic Therapeutics and Diagnostics
5/5/2009E-092-2008/0Novel Oligonucleotides for Treatment of Human Cancer
5/4/2009E-257-2004/0Modulating Expression of the Metastasis Suppressor MxA
5/4/2009E-223-2006/1
E-284-2008/0
Small-Molecule TSH Receptor Modulators for Diagnosis and Treatment of Thyroid Disease and Cancer
5/4/2009E-045-2009/0Treating Cancer through Immunotherapy with Herceptin-Based Receptors Specific for ErbB2 (Her2/Neu)
5/4/2009E-336-2008/0Peptides for Treating Mesothelin- and/or CA125-Expressing Cancers
5/4/2009E-324-2008/0Selective Killing of Cancer Cells By Inhibition of Geminin
5/4/2009E-053-2006/0Polyclonal Antibody Against Bloom's Syndrome Protein (BLM) for Research and Diagnostic Use
5/4/2009E-193-1997/06,555,367Targeted Recombinant Adenoviral Vectors
3/23/2009E-247-2008/0Lasonolide Compounds as Reagents for Inducing Premature Chromosome Condensation and Methods of Treating Cancer
2/25/2009E-302-2008/0Prevention of Head and Neck Cancer Using Rapamycin and Its Analogs
2/2/2009E-185-2008/0HMGN Polypeptides as Immune Enhancers and HMGN Antagonists as Immune Suppressants
2/2/2009E-123-2008/0Substituted IL-15
1/9/2009E-182-2008/0Method of Treating Pneumoconiosis with Oligodeoxynucleotides
1/9/2009E-278-2007/0Attenuated Salmonella as a Delivery System for siRNA-Based Tumor Therapy
1/5/2009E-295-2008/0Novel Inhibitor of NF-kappa B Pathway
1/1/2009E-274-2008/0Monoclonal Antibodies to the Tumor-Specific Antigen, Human ROR1
1/1/2009E-051-2008/0A Novel and Efficient Technology for Targeted Delivery of siRNA
12/1/2008E-003-2008/0A Novel, Non-Invasive and Therapeutically Useful High Throughput Technique to Isolate Highly Enriched Tumor Reactive Lymphocytes from Peripheral Blood - Potential Use in Adoptive Immunotherapy
12/1/2008E-034-2002/07,365,160Mutant Nuclear Orphan Receptor for Drug Metabolism Assays
11/1/2008E-211-2008/0Fully Human Anti-Human Monoclonal Antibody Helpful in Developing Therapies Against Autoimmune and Infectious Diseases and Cancer
11/1/2008E-250-2007/0Induced Internalization of Surface Receptors
11/1/2008E-166-2007/0Discovery of and Use of Fragments of DOC1 as Antiangiogenic and Antitumor Therapy
11/1/2008E-174-2008/0Therapeutic Targeting of CSN5, a Negative Regulator of p53 and p27, in Human Hepatocellular Carcinoma
11/1/2008E-256-1999/0Methods for Accurately Measuring and Regulating Bound Adrenomedullin
10/1/2008E-065-2008/0Association of the ECHDCI/RNF146 Gene Region on Human Chromosome 6q with Breast Cancer Risk and Protection
9/1/2008E-163-2007/0Bifunctional Compounds that Bind to Hormone Receptors
9/1/2008E-175-2008/0Over-expression and Mutation of a Tyrosine Kinase Receptor FGFR4 in Tumors
9/1/2008E-332-2007/0Small Molecule Inhibitors of c-Met
9/1/2008E-139-1999/07,081,518A Novel Recombinant Immunotoxin SS1P (anti-mesothelin dsFv-PE38): A Therapeutic Treatment for Lung Cancer and Other Mesothelin Expressing Cancers
9/1/2008E-147-2008/0Cyclized NGR Peptide for Tumor Targeting
9/1/2008E-213-2001/27,361,664Vitamin D Receptor Antagonists for Treating Breast Cancer
8/1/2008E-249-2005/0Methods of Treating and Preventing Renal Cancer using a Dimethane Sulfonate Compound
8/1/2008E-285-2006/2New Tumor Endothelial Markers: Genes that Distinguish Physiological and Pathological Angiogenesis
8/1/2008E-062-1996/0
E-099-1996/0
E-154-1998/0
E-200-1990/3
E-200-1990/4
E-256-1998/0
E-256-1998/1
E-259-1994/3
E-259-1994/4
E-260-1994/1
6,001,349
6,045,802
6,165,460
6,319,496
6,548,068
6,756,038
6,893,869
6,946,133
6,969,609
7,118,738
7,211,432
7,368,116
7,410,644
7,547,773
7,598,225
Enhanced T-cell Activation by Costimulation: A Potentially Novel Approach for the Prevention and/or Therapy of Cancer (Excluding Prostate Diseases and Melanoma) and for Infectious Diseases
8/1/2008E-194-2008/0Immunotoxins Made with Modified Cholix Toxin and Uses Thereof
8/1/2008E-274-2003/02-Amino-O4-Substituted Pteridines: Improved Chemotherapy Adjuvants
8/1/2008E-262-2000/0
E-262-2000/1
6,977,241
7,425,537
SH2 Domain Binding Inhibitors
7/1/2008E-282-2007/0TGF-beta Gene Expression Signature in Cancer Prognosis
7/1/2008E-150-2007/0A Novel Therapeutic Strategy for the Treatment of Hyperpigmentation and Melanoma
7/1/2008E-263-2004/0A New Pot1 Variant Gene as a Diagnostic Biomarker for Hereditary Non-polyposis Colorectal Cancer
7/1/2008E-321-2006/0Treatment of Skin Conditions Using DKK1
6/1/2008E-292-2007/0Immunotoxins with Deletions in Domain II that Remove Immunogenic Epitopes with Minimal Loss of Cytotoxic Activity
5/1/2008E-096-2000/07,531,352The Use of an Inducible Plasmid Vector Encoding for Active TGF-beta for the Treatment of Autoimmune Diseases
5/1/2008E-120-2003/27,378,276Method of Inducing Memory B Cell Development and Terminal Differentiation
5/1/2008E-080-2008/0Human and Improved Murine Monoclonal Antibodies Against CD22
5/1/2008E-079-2008/0Human Monoclonal Antibody Against Mesothelin
5/1/2008E-129-2008/0Synthetic Analogs of Juxtamembrane Domain of IGF-1 Receptor as Anti-Cancer Agents
5/1/2008E-265-1999/2Inhibition of Cell Motility, Angiogenesis and Metastasis
5/1/2008E-316-2007/0Method of Inhibiting ABCG2 and Related Treatments
5/1/2008E-265-2007/0Telomerase Suppressor Compositions and Methods for Diagnosis and Treatment of Cancer
5/1/2008E-206-1995/36,320,022
7,101,548
Treatment and Diagnosis of Cancer, Diabetes and other Disorders Using Adrenomedullin Peptides and Antibodies
4/1/2008E-003-2007/0Engineered Human Antibody Constant Domains (Nanoantibodies) as Scaffolds for Binders
2/1/2008E-137-2006/0
E-137-2006/1
Manganese Superoxide Dismutase VAL16ALA Polymorphism Predicts Resistance to Doxorubicin Cancer Therapy
2/1/2008E-019-2005/0Synergistic Effect of TGF-beta Blockade and Immunogenic Agents on Tumors
2/1/2008E-315-2007/0New Inhibitors of Multidrug Resistant Proteins Such As ABCG2
2/1/2008E-208-2007/0Eeyarestatins: Novel Deubiquitination Inhibitors for the Treatment of Drug-Resistant Cancers
2/1/2008E-203-2000/07,144,918Biologically Active Macrolides, Compositions and Uses Thereof
1/1/2008E-084-1991/13715313
6,274,134
684806
Antibodies and Polypeptides Specific to AAMP-1: Diagnostic and Therapeutic Uses Thereof
1/1/2008E-108-2007/0Photosensitization by Nuclear Receptor-Ligand Complexes and Cell Ablation Uses Thereof
1/1/2008E-008-2008/0Diagnosis and Treatment of Barrett's Esophagus and Associated Esophageal Adenocarcinoma
12/1/2007E-168-2007/0Treatment for Chronic Inflammatory Disease and Cancer by Inhibition of MMP-1
11/1/2007E-074-2007/0Human T-box Transcription Factor Brachyury as a Target for Cancer Immunotherapy: Identification of Epitopes of Human Brachyury as Targets for T-cell Mediated Lysis of Tumors
11/1/2007E-177-2006/07,553,936A Novel, Inhibitory Platelet Surface Protein (TREM Like Transcript, TLT-1): New Target for the Treatment of Cancer, Infectious Diseases, Cardiac Diseases, and Platelet-Associated Disorders
11/1/2007E-061-2007/0Diagnostic Ovarian Cancer Biomarkers
11/1/2007E-139-1999/07,081,518A Clinically Proven Therapeutic Treatment and Diagnostic Tool for Mesothelin Expressing Cancers: A Novel Recombinant Immunotoxin SS1P (anti-mesothelin dsFv-PE38)
11/1/2007E-302-2007/0A Family of Small Molecules for Selective Inhibition of Wip1 Phosphatase
11/1/2007E-232-1995/0
E-232-1995/1
5,658,744
5,965,366
A New Method for Determining Level of Immunosuppression in Humans
11/1/2007E-135-2006/1
E-303-2003/0
Inactivation of Enveloped Viruses and Tumor Cells for Infectious Disease and Cancer Vaccines
10/1/2007E-064-2005/0Biomarkers for Tissue Status
10/1/2007E-084-2007/0Use of HDAC Inhibitors for the Prevention and Cure for Brain Metastases of Cancers
9/1/2007E-137-2005/0Methods and Compositions for Treating FUS1 Related Disorders
9/1/2007E-200-2007/0New and Improved Chemotherapy Adjuvants: Folate Based Inactivators of O6-alkylguanine-DNA alkyltransferase (alkyltransferase)
9/1/2007E-272-1998/06,790,948
7,431,926
Tumor Suppressor Genes
9/1/2007E-161-2007/0Treatment of Primary Tumors and Tumor Metastases with TNF-alpha Antagonists
9/1/2007E-153-1998/07,256,256Peptide Inhibitor of Cyclin Dependent Kinase 4 (CDK4) Derived from MyoD
8/1/2007E-080-2006/0A New Series of Thalidomide Analogs That Have Potent Anti-Angiogenic Properties
8/1/2007E-104-2006/0Immunogenic Peptides and Methods of Use for Treating Prostrate and Uterine Cancers
8/1/2007E-028-1999/07,399,827Diagnostic and Therapeutic Methods of Detecting and Treating Cancers of Reproductive Tissues
8/1/2007E-215-2007/0Methods for Determining Hepatocellular Carcinoma Subtype and Detecting Hepatic Cancer Stem Cells
8/1/2007E-068-1998/06,685,933
7,235,232
Interferon Alpha Hybrids
8/1/2007E-180-2000/06,939,547
7,108,981
7,235,365
7,374,756
Specific Binding Agents for KSHV vIL-6 that Neutralize a Biological Activity
7/1/2007E-118-2005/0A Gene Therapy to Treat Lung Cancer
7/1/2007E-265-2005/0Modification of Recombinant Anti-tumor RNase (rapLR1) for Optimal Use in the Large Scale Manufacture of Stable and Potent RapLR1-Antibody Conjugates
7/1/2007E-288-2006/0Cyclic Phosphopeptide Inhibitors of Protein Phosphatase 2C Delta, Wip1
6/1/2007E-117-2006/0Diagnostic and Therapeutic Use of Brother of the Regulator of Imprinted Sites (BORIS) Alternative Splice Forms
6/1/2007E-042-1998/06,897,018
7,534,565
DLC-1 Gene Deleted in Cancers
6/1/2007E-098-2007/0Synthetic Macrolides Inhibit Breast Cancer Migration
6/1/2007E-012-1991/0
E-012-1991/2
E-044-1997/0
E-044-1997/1
5,167,956
5,725,857
6,632,928
Immunotoxin with in-vivo T cell Suppressant Activity
6/1/2007E-060-2007/0A Gene Expression Profile that Predicts Ovarian Cancer Patient Response to Chemotherapy
6/1/2007E-160-2006/0Potent, Easy to Use Targeted Toxins as Anti-Tumor Agents
6/1/2007E-012-1991/0
E-012-1991/4
E-012-1991/7
E-044-1997/0
E-044-1997/1
E-059-1998/0
E-168-1999/0
5,167,956
5,762,927
6,103,235
6,632,928
7,288,254
Methods of Inducing Immune Tolerance Using Immunotoxins
6/1/2007E-310-2001/0Identification of Ovarian Cancer Tumor Markers and Therapeutic Agents
5/1/2007E-082-2005/0
E-082-2005/2
Sipa-Gene and Sipa-1 Inhibitor for the Diagnosis and Treatment of Metastatic Cancer
5/1/2007E-019-2000/0
E-019-2000/1
E-019-2000/2
Inhibition of ABC Transporters by Transmembrane Domain Analogs
5/1/2007E-018-2005/2Diagnosing and Treating Cancer Using beta-Catenin Splice Variants
5/1/2007E-287-2004/1Novel Diagnostics and Therapeutics for Various Hematologic Malignancies: Monoclonal Antibodies to Members of Fc receptor-like (FCRL) Proteins
5/1/2007E-070-2005/0Inhibitors of Ubiquitin E1
5/1/2007D-001-1996/1
D-001-2006/0
D-003-1992/2
D-003-1992/3
D-004-1992/0
D-004-1992/1
E-259-1998/2
5,472,693
5,877,291
5,892,020
6,051,225
6,071,515
6,207,815
6,329,507
6,348,581
6,737,060
6,737,061
6,752,990
6,753,152
6,753,420
6,818,749
628078
7,256,004
Humanized Anti-Carcinoma CC49 Monoclonal Antibodies
5/1/2007E-062-1996/0
E-099-1996/0
E-154-1998/0
E-200-1990/3
E-200-1990/4
E-256-1998/0
E-256-1998/1
E-259-1994/3
E-259-1994/4
E-260-1994/1
6,001,349
6,045,802
6,165,460
6,319,496
6,548,068
6,756,038
6,893,869
6,946,133
6,969,609
7,118,738
7,211,432
7,368,116
7,410,644
7,547,773
7,598,225
Enhanced T-cell Activation by Costimulation: An Effective Immunotherapy for Cancer and Infectious Diseases
5/1/2007E-307-2004/1Aminoalkyl Substituted O6-Benzylguanine Derivatives as Inactivators of O6-Alkylguanine-DNA Alkyltransferase and Adjuvants for Chemotherapy
4/1/2007E-059-2007/2New Mouse T Cell Receptors as Potential Therapeutic Agents for the Treatment of Metastatic Cancer
4/1/2007E-271-2006/0A Novel DNA Vaccine for the Treatment of Malignancies Expressing Immature Laminin Receptor Protein
4/1/2007E-103-2000/0
E-103-2000/1
E-103-2000/2
E-305-2005/0
6,753,317
6,916,905
Novel Dmt-Tic Analogues Specific for Delta- and Mu-Opioid Receptors
3/1/2007E-323-2004/0Arylthioindole Tubulin Polymerization Inhibitors and Methods of Treating or Preventing Cancer Using Same
3/1/2007E-314-2003/0
E-314-2003/1
E-314-2003/2
Identification and Isolation of the Receptor for Pigment Epithelium-derived Factor (PEDF)
3/1/2007E-148-2003/07,572,887Genes Expressed in Prostate Cancer and Methods of Use
2/1/2007E-107-1998/06,562,347Methods and Compositions of Chemokine-Tumor Antigen Fusion Proteins as Cancer Vaccines
2/1/2007E-070-2007/2Human Cancer Therapy Using Engineered Anthrax Lethal Toxin
2/1/2007E-138-2006/0Highly Soluble Pyrimido-Dione-Quinoline Compounds: Small Molecules that Stabilize and Activate p53 in Transformed Cells
2/1/2007E-317-2004/1Metal Chelators and Target-Moiety Complexes for Imaging
1/1/2007E-132-2006/0
E-132-2006/1
E-132-2006/2
A New Method for Improving the Therapeutic Efficacy of L-Asparaginase in Multiple Types of Cancer
1/1/2007E-213-1987/15,616,471Methods for Assaying Hair Follicle Growth and Development
1/1/2007E-183-2004/1Enriched Natural Killer Cells for Adoptive Infusion Cancer Therapy
12/1/2006E-347-2004/0ARH3, a Therapeutic Target for Cancer, Ischemia, and Inflammation
12/1/2006E-014-2007/0Peptide and Peptidomimetic Inhibitors of Smoothened Protein as Anti-neoplastic Agents
12/1/2006E-125-2006/1Extracellular Matrix/Metastasis Modifier Genes as a Method for Characterization and Prevention of Metastatic Tumor
12/1/2006E-311-2006/1Chitosan as a Universal Vaccine Adjuvant, Antigen Depot and Cytokine Depot
10/1/2006E-027-2006/0PDE11A as a Novel Therapeutic Target for Inherited Form of Cushing Syndrome and Endocrine Tumors
9/1/2006E-200-2006/0Mammalian Cell Surface Display of Fvs for Rapid Antibody Maturation
9/1/2006E-265-1997/07,084,239Cancer Peptides of NY-ESO-1/CAG-3
8/1/2006E-340-2004/0
E-340-2004/2
Adoptive Immunotherapy with T Lymphocytes Engineered for Enhanced Survival
8/1/2006E-201-2006/1Diagnostic and Therapeutic Strategies for Metastatic Hepatocellular Carcinoma by Targeting Osteopontin
8/1/2006E-086-2006/0Hybrid T-Cell Receptors for the Development of Improved Vaccines
6/1/2006E-097-2006/0
E-097-2006/1
Use of Tetracyclines as Anti-Cancer Agents
6/1/2006E-091-2004/0Ultrasonic Waves with Nanovessels or Tethered Nanotube/Monoclonal Antibody Composites for Cancer Therapy
6/1/2006E-090-2004/0Radio-Activated Boron-Nitride Nanotube-Antibody Conjugates for Cancer Therapy and Diagnostics
6/1/2006E-122-2006/0Agonist Epitopes for Renal Cell Carcinoma
6/1/2006E-336-2005/0Novel Human IGF-1 Specific IGF-I and IGF-II Cross-Reactive Human Monoclonal Antibodies as Potential Anti-tumor Agents
6/1/2006E-165-2006/0Diamidine Inhibitors of Tdp1 as Anti-Cancer Agents
6/1/2006E-053-1996/06,982,168Immortal Human Prostate Epithelial Cell Cultures as a Prostate Cancer Model
5/1/2006E-200-2005/0Insect Cell Production of Recombinant Adeno-Associated Virus that Produce Cytotoxic Gene Products and Applications for Solid Tumor Therapy
5/1/2006E-139-2005/0Identification of a Novel Folliculin Interacting Protein, FNIP-1
5/1/2006E-106-2006/3T-cell Receptor Recognizing Renal Cell Carcinoma
5/1/2006E-094-2006/0Preparation of a Peptide Targeted Human RNase, RGD-Eosinophil Derived Neurotoxin (RGD-EDN) To Specifically Target Tumor Vasculature
5/1/2006E-090-2006/0Adoptive Immunotherapy with Autologous Natural Killer Cells
5/1/2006E-055-1999/06,680,176Identification of Candidate Ligands which Modulate Antigen Presenting Cells
5/1/2006E-176-1998/1Anti-Notch-1 Monoclonal Antibodies for Inducing Cellular Differentiation and Apoptosis
3/1/2006E-319-2005/0Methods of Treating Cancer Using Pyridine Carboxaldehyde Pyridine Thiosemicarbazone Radiosensitizing Agents
3/1/2006E-262-1999/17,459,536Monoclonal Antibodies Which Specifically Bind to the Ligand Hepatocyte Growth Factor (HGF) and are Useful in the Treatment of Cancer
3/1/2006E-312-2005/0Immunogenic Peptides and Methods of Use for Treating and Preventing Cancer
2/1/2006E-146-1992/06,040,334Use of Inhibitors of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase as a Modality in Cancer Therapy
2/1/2006E-218-2005/0Methodology for Large Scale Manufacture of Stable Disulfide-Conjugated Antibody-Ribonuclease
2/1/2006E-106-2005/0Identification of Biomarkers by Serum Protein Profiling
2/1/2006E-065-2002/0ELISA Assay of Serum Soluble CD22 to Assess Tumor Burden/Relapse in Subjects with Leukemia and Lymphoma
2/1/2006E-104-1998/06,060,458Oligodeoxyribonucleotides Comprising O6-Benzylguanine and Their Use
1/1/2006E-163-2005/0Intraperitoneal Injection of Pseudovirions Carrying a Toxin Leads to Significantly Reduced Tumor Size
1/1/2006E-067-1995/05,610,185Treatment of Hyperproliferative Epithelial Skin Diseases by Topical Application of Hydroxylated Aromatic Protein Cross-Linking Compounds
1/1/2006E-014-1991/07,056,908Pharmaceutical Compositions and Methods for Preventing Skin Tumor Formation and Causing Regression of Existing Tumors
12/1/2005E-058-2005/0Synthesis of Indenoisoquinoliniums and Methods of Use
12/1/2005E-323-2003/07,589,181Minimally Immunogenic Variants of SDR-Grafted Humanized Antibody CC49 and Their Use
12/1/2005E-142-1990/25,731,167
6,084,069
6,417,338
Autotaxin: Motility Stimulating Protein Useful in Cancer Diagnosis and Therapy
12/1/2005E-003-2006/0Antibodies and Immunotoxins that Target Human Glycoprotein NMB
12/1/2005E-142-2005/0A Single Ribozyme to Catalyze both Trimming and Transacting Catalysis - Potential Therapeutic for HPV Infection and Cervical Cancer
11/1/2005E-217-2005/0Antibodies Against Insulin-Like Growth Factor II and Uses Thereof
11/1/2005E-272-2002/0
E-272-2002/1
7,439,226Serine Protease Inhibitors
11/1/2005E-192-2004/0Compositions and Methods for Diagnosis and Treatment of Chemotherapy-Resistant Neoplastic Disease
10/1/2005E-065-2005/0Novobiocin Analogues as Anticancer Agents
10/1/2005E-266-1994/16,428,788Compositions and Methods of Specifically Targeting Tumors
10/1/2005E-110-1992/05,272,146
5,441,941
1,2-Dihydroellipticines with Activity Against CNS-Specific Cancer Cell Lines
10/1/2005E-262-2005/0Mutated Pseudomonas Exotoxins with Reduced Antigenicity
10/1/2005E-167-1997/07,153,866The Use of Nitroxides in the Prophylactic and Therapeutic Treatment of Cancer Due to Genetic Defects
10/1/2005E-081-2001/0
E-081-2001/1
E-081-2001/2
Zebularine, A Stable and Orally Active Inhibitor of Cytosine DNA Methyltransferase Capable of Reactivating Dormant Tumor Suppressor and Inhibiting Tumor Growth
9/1/2005E-327-2004/0A New Approach Toward Macrocyclization of Peptides
9/1/2005E-181-1999/07,208,313A Combined Growth Factor-Deleted and Thymidine Kinase-Deleted Vaccinia Virus Vector for Cancer Therapy
9/1/2005E-144-2005/0Soluble Fragments of the IGF1R Ectodomain
9/1/2005E-121-2005/0Polymer-linked Pseudomonas Exotoxin Immunotoxin
9/1/2005E-095-2000/2Amelioration of Inflammatory Arthritis Targeting the Pre-ligand Assembly Domain (PLAD) of Tumor Necrosis Factor Receptors
9/1/2005E-087-1996/0Heterologous Boosting Immunizations
9/1/2005E-009-1991/0
E-009-1991/1
E-301-1998/2
5,217,953
5,565,424
Cancer Therapy Using Vasoactive Intestinal Peptide Antagonists
9/1/2005E-315-2003/0SH2 Domain Binding Inhibitors (E-315-2003)
9/1/2005E-013-1998/06,943,191Disubstituted Lavendustin A Analogs and Pharmaceutical Compositions Comprising the Analogs
9/1/2005E-060-2002/2DNA-Binding Polyamide Drug Conjugates
9/1/2005E-188-1998/16,136,992Novel 2-Alkoxy Estradiols and Derivatives Thereof
9/1/2005E-244-1997/0
E-244-1997/3
6,353,019
7,381,744
Antitumor Macrocyclic Lactones / Vacuolar-Type (H+)-ATPase-Inhibiting Compounds and Uses Thereof
9/1/2005E-291-2003/0New Building Blocks for DNA Binding Agents
8/1/2005E-155-2005/0
E-155-2005/1
E-155-2005/2
E-155-2005/3
Immunogenic Peptides From Human Papillomavirus Type 16 E2
8/1/2005E-046-2005/0A Novel Interleukin-12 (IL-12) Inducing Protein Isolated from Toxoplasma gondii Inflammatory Profilin (TGIP)
8/1/2005E-140-2005/0Induction of C/EBPalpha and Uses Thereof
8/1/2005E-131-2000/0Methods for Reducing Tumor Growth and Metastasis by Inhibiting MCP-1 Activity
8/1/2005E-130-1993/05,861,156Methods of Delivering Agents to Target Cells
7/1/2005E-132-1988/0Use of 8-C1-cAMP as Anticancer Drug
7/1/2005E-208-2005/0Anti-CD30 Antibodies that Bind to Intact CD30 but not to Soluble CD30
7/1/2005E-279-1999/06,812,246Aminoflavone Prodrug
7/1/2005E-075-2004/2Methods for the Identification and Use of Compounds Suitable for the Treatment of Drug Resistant Cells
6/1/2005E-339-2004/0Framework Residue Substituted Humanized COL-1 Antibodies and Their Use
6/1/2005E-106-2004/0Compositions Comprising T Cell Receptors and Methods of Use Thereof
6/1/2005E-158-2005/0Identification of H2-Db and HLA-A2 Specific CD8 Epitopes from Human KDR/VEGFR-2 that Inhibit Angiogenesis by Vaccination
6/1/2005E-135-2002/17,470,775Novel Anti-CD30 Antibodies and Recombinant Immunotoxins Containing Disulfide-Stabilized Fv Fragments
6/1/2005E-320-2001/07,141,589Compositions and Methods for Inhibiting Vascular Channels and Methods of Inhibiting Proliferation
5/1/2005E-245-2004/0Methods of Reducing the Activity and Concentration of an Eph Receptor Tyrosine Kinase
5/1/2005E-199-1999/0Mycolactone and Related Compounds
4/1/2005E-265-1994/0
E-265-1994/1
6,255,105
6,342,392
6,737,251
7,067,635
Nucleotide and Deduced Amino Acid Sequences of a New Tumor Gene, Int6
4/1/2005E-163-1991/26,797,492Method for Reducing the Immunogenicity of Antibody Variable Domains
4/1/2005E-107-2005/0Methods for Tumor Treatment Using Dendrimer Conjugates
4/1/2005E-117-2005/0Aminoglycosides and Ribosome Inhibitors as Inhibitors of Tyrosyl-DNA-Phosphodiesterase
4/1/2005E-072-2005/0Inhibition of Proteosome Function to Potentiate the Proapoptotic and Antitumor Activity of Cytokines
4/1/2005E-070-1982/25,656,587
5,705,477
Compositions of Transforming Growth Factor Beta (TGF-beta) Which Promotes Wound Healing and Methods for Their Use
4/1/2005E-190-2002/27,485,709Identification of Novel Birt-Hogg-Dubé (BHD) Gene
4/1/2005E-150-2001/17,175,838Use of a Promoter of T-cell Expansion and an Inducer of CD40 Stimulation in the Treatment or Prevention of a Pathologic State
3/1/2005E-001-2005/0Carbohydrate-Encapsulated Gold Nanoparticles as Novel Anti-Metastatic Agents
3/1/2005E-206-1992/15,610,053Chromatin Insulator Protecting Expressed Genes of Interest for Human Gene Therapy or Other Mammalian Transgenic Systems
3/1/2005E-101-2005/0Karyotypic Complexity as a Determinant of Anti-Cancer Drug Activity
3/1/2005E-079-2005/0Inhibition of Human Papillomavirus Type 16 and 18 E6 and E7 Oncogene Expression by E6 and E7-specific siRNAs
3/1/2005E-090-1987/0Water-Soluble, Antineoplastic Derivatives of Taxol
3/1/2005E-105-2004/0
E-105-2004/1
Minimally Immunogenic Germline Sequence Variants of COL-1 Antibody and Their Use
2/1/2005E-025-2003/0
E-025-2003/1
Methods for Prophylaxis and Treatment of HER-2/neu Tumors
1/1/2005E-287-2004/0
E-287-2004/1
Mabs to IRTA2 for Use in Diagnosis and Therapy of IRTA-Expressing Cancers
1/1/2005E-123-2001/0
E-124-2001/1
7,247,615Peptide Agonists of Prostate-Specific Antigen and Uses Thereof
1/1/2005E-259-2003/0Anti-Proliferative Activity of an Unexpected mTOR Kinase Inhibitor
1/1/2005E-191-2003/1Eosinophil-Derived Neurotoxin, an Antimicrobial Protein with Ribonuclease Activity, is an Immunostimulant
1/1/2005E-331-2002/0Activation of Recombinant Diphtheria Toxin Fusion Proteins by Specific Proteases Highly Expressed on the Surface of Tumor Cells
1/1/2005E-116-2003/07,541,035Immunogenic Peptides for the Treatment of Prostate and Breast Cancer
1/1/2005E-051-2003/0Recombinant Immunotoxin and Use in Treating Tumors
12/1/2004E-071-2000/06,468,524AAV4 Vector and Uses Thereof
12/1/2004E-072-2000/06,855,314AAV5 Vector for Transducing Brain Cells and Lung Cells
10/1/2004E-059-2004/0Multimeric Protein Toxins to Target Cells Having Multiple Identifying Characteristics
10/1/2004E-220-1993/15,744,492Method for Inhibiting Angiogenesis
9/1/2004E-311-2003/0Use of Protein Kinase C Delta Inhibitor, Specifically Rottlerin, Alone or in Further Combination with Staurosporine, in the Treatment of Metastatic Epithelioid Melanoma
8/1/2004E-040-1996/06,734,014
7,378,277
Methods and Compositions for Transforming Dendritic Cells and Activating T Cells
8/1/2004E-325-2001/1
E-325-2001/2
6,723,551
7,271,002
Production of Adeno-Associated Viruses in Insect Cells
8/1/2004E-007-2004/07,511,032Adduct Compounds of Pyrrolobenzodiazepinones, Compositions Comprising the Same and Methods Related Thereto
8/1/2004E-074-2004/0Methylation Inhibitor Compounds
8/1/2004E-230-1999/06,696,436B-Homoestra-1,3,5(10)-trienes as Modulators of Tubulin Polymerization
7/1/2004E-090-2003/0Vaccine Peptide Derived from XAGE-1 to Prevent Tumor Growth
6/1/2004E-112-1994/05,652,223
5,981,712
6,790,936
DNA Encoding CAI Resistance Proteins and Uses Thereof
6/1/2004E-325-2002/0Antibodies That Bind POTE and Uses Thereof
5/1/2004E-321-2000/0Novel Antisense Oligonucleotides Targeting Folate Receptor Alpha
5/1/2004E-002-2002/17,456,268Materials and Methods for Inhibiting Wip1
4/1/2004E-133-2004/0Carbohydrate-Encapsulated Quantum Dots For Cell-Specific Biological Imaging
4/1/2004E-326-2002/0
E-326-2002/2
Triplex Hairpin Ribozyme
4/1/2004E-008-2004/0Therapeutic Administration of the Scrambled Anti-Angiogenic Peptide C16Y
3/1/2004E-240-1993/06,699,842Dominant Negative Deletion Mutants Of C-Jun And Their Use In The Prevention And Treatment Of Cancer
3/1/2004E-231-2002/07,498,336Deazaflavin Compounds and Methods of Use Thereof
3/1/2004E-135-1989/0
E-146-1999/0
5,696,237
5,863,745
6,051,405
7,521,054
LMB-2, An Immunotoxin That Shows Efficacy in Phase I Clinical Trials in Treating Patients with Chemotherapy-Resistant Hairy Cell Leukemia and Other Hematologic Malignancies
2/1/2004E-244-2002/0Glioma-Selective Polypeptides, Alone or Coupled to a Therapeutic/Diagnostic Agent, Compositions Comprising Same, and Uses Thereof
2/1/2004E-037-2001/1Use of IL-13 Inhibitors to Prevent Tumor Recurrence
12/1/2003E-297-2002/07,381,405Methods of Preparing Lymphocytes that Express Interleukin-2 and Their Use in the Treatment of Cancer
12/1/2003E-227-2002/0Targeting of the Hepatitis A Cellular Receptor to Treat Renal Cancer
12/1/2003E-189-2003/0Thalidomide Analogs
12/1/2003E-230-2000/07,432,236Vasostatin as Marrow Protectant
11/1/2003E-253-2003/0Cytotoxic Indeno- and Isoindenoisoquinoline Compounds
11/1/2003E-342-2002/0beta-Defensins as Activators of Dendritic Cells and Vaccine Carrier
11/1/2003E-083-2003/0Intracellular Trapping of Radionuclides by Enzyme-Mediated Reduction
11/1/2003E-253-2002/0Compositions and Methods for Detecting Abnormal Cell Proliferation
11/1/2003E-008-2001/07,598,077Compositions and Methods for Enhancing Differential Gene Expression
11/1/2003E-537-1983/2
E-970-1997/0
Leukoregulin, An Antitumor Lymphokine, and Its Therapeutic Uses
11/1/2003E-169-2003/0Geldanamycin Derivatives with Methyl Substituted Hydrogen Atom at the N22 Position as Anti-Cancer Agents
10/1/2003E-001-2003/0
E-001-2003/1
E-019-2003/0
Methods and Materials for Controlling Stem Cell and Cancer Cell Proliferation and Differentiation
10/1/2003E-294-2002/07,462,593A New Target for Angiogenesis and Anti-Angiogenesis Therapy
9/1/2003E-224-2002/0Novel Anti-Tumor and Anti-Fungal Compounds Isolated from Plants of the Genus Aniba
9/1/2003E-016-2000/0Cloning and Characterization of VIAF in Several Organisms
8/1/2003E-063-2003/0Rapamycin Resistant T Cells and Therapeutic Uses Thereof
6/1/2003E-065-1996/2
E-289-1999/0
6,187,775
6,541,483
6,664,263
Imidazoacridones with Anti-Tumor Activity
6/1/2003E-091-2002/07,329,502Zap70 Protein Expression as a Marker for Chronic Lymphocytic Leukemia (CLL)
5/1/2003E-097-2003/0Triggering Receptors Expressed in Myeloid Cells (TREM) Like Transcript (TLT-1), A Novel Inhibitory Receptor of Platelets and Uses Therefore
5/1/2003E-256-2002/017-AAG Treatment of Diseases Sensitive to c-KIT Down Regulation
4/1/2003E-191-2002/07,521,475Chondropsin-Class Antitumor V-ATPase Inhibitor Compounds, Compositions and Methods of Use Thereof
4/1/2003E-063-2002/07,081,452
7,163,935
Scorpionate-Like Pendant Macrocyclic Ligands, Complexes and Compositions Thereof, and Methods of Using Same
4/1/2003E-060-2000/0
E-060-2000/1
4248600
7,488,710
sFRP and Peptide Motifs That Interact with sFRP and Methods of Their Use
3/1/2003E-138-2001/07,618,789Use of Semenogelin in the Diagnosis, Prognosis, and Treatment of Cancer
3/1/2003E-057-1994/25,844,075
6,270,778
6,537,560
6,965,017
7,232,887
7,612,044
gp100 Cancer Antigens
3/1/2003E-052-2002/0Tumor Suppressor Gene Polypeptides and Related Nucleic Acids, Host Cells, Compositions, and Methods of Use in Inhibition of Cell Growth, Modulation of Gene Expression, and Enhancement of Immune-Response Inducing Effect of a Vaccine
1/1/2003E-239-2002/0Minimally Immunogenic Variant of Humanized COL-1 Antibody Against Carcinoembryonic Antigen (CEA)
12/1/2002E-156-1999/0Pyrimidine Phosphorylase as a Target for Imaging and Therapy
12/1/2002E-013-2002/07,569,673Humanized Anti-TAG 72 CC49 for Diagnosis and Therapy of Human Carcinomas
11/1/2002E-198-2001/0Use of a Histone Deacetylase Inhibitor to Increase the Entry of an Adenoviral Agent into a Cell
11/1/2002E-196-2001/0Use of Interferon-Inducible 2',5'-Oligoadenylate-Dependent RNase in the Diagnosis, Prognosis, and Treatment of Prostate Cancer
11/1/2002E-223-1992/05,359,078
5,482,954
5,498,620
5,705,514
Signal Transduction Inhibitor Compounds in Clinical Trials as Cancer Therapeutics
9/1/2002E-048-2002/0Antiproliferative Actions of Human IGF Binding Protein-3 Mutants That Do Not Bind IGF-I or IGF-II
9/1/2002E-300-2001/07,432,349New Tumor Suppressor Gene, p28ING5
8/1/2002E-132-1994/05,942,230
6,197,528
Retinoids Can Increase the Potency of Anti-Cancer Immunotoxins
7/1/2002E-069-2001/06,756,399Use of Lipoxygenase Inhibitors and PPAR Ligands as Anti-Cancer Therapeutic and Intervention Agents
7/1/2002E-129-2001/07,355,012Mutated Anti-CD22 Antibodies with Increased Affinity to CD22-Expressing Leukemia Cells
5/1/2002E-225-2001/0MRP8, A Member of the ABC Transporter Superfamily Highly Expressed in Breast Cancer, and Uses Thereof
5/1/2002E-151-2001/0Method of Promoting Engraftment of a Donor Transplant in a Recipient Host
5/1/2002E-344-2001/0The Ovachip: A Clinically Useful cDNA Array for Differential Diagnosis of Ovarian Cancer
4/1/2002E-099-2001/0Mitochondrial Topoisomerase I
4/1/2002E-051-2002/1Methods for Using Modulators of Extracellular Adenosine or an Adenosine Receptor to Enhance Immune Response and Inflammation
4/1/2002E-323-2000/0Activated Dual Specificity Lymphocytes and Their Methods of Use
3/1/2002E-360-2001/0Generation and Use of Tc1 and Tc2 Cells
1/1/2002E-161-2000/0XAGE-1, A Gene Expressed in Multiple Cancers and Uses Thereof
1/1/2002E-286-2000/0Histone Deacetylase Inhibitors in Diagnosis and Treatment of Thyroid Neoplasms
1/1/2002E-086-2001/0
E-086-2001/1
7,419,957Novel Peptides to a Melanoma Antigen and Their Use in Diagnostic and Therapeutic Methods
1/1/2002E-002-2001/0Tumor Antigen Homologous to Poly(A) Polymerase
11/1/2001E-088-2001/0Diacylglycerol Compounds Useful as Protein Kinase C Activators and Apoptosis Inducers
9/1/2001E-033-2001/07,476,535New Isoform of Tyrosinase-Related Protein (TRP-2) that Contains an HLA-A2 Restricted Epitope
8/1/2001E-123-2000/0Method of Treating Cutaneous T-Cell Lymphoma by Administering a Histone Deacetylase Inhibitor
6/1/2001E-053-2001/0PRAC & PRAC-Y: Small Nuclear Proteins Found in Prostate and Colon Cancer, and Uses Thereof
5/1/2001E-203-1994/05,693,779Production and Use of Anti-Dorsalizing Morphogenetic Protein
4/1/2001E-011-1994/05,861,158Immunization from an Immunized Allogeneic Bone Marrow Donor
4/1/2001E-149-2000/06,756,215Biologically Active FLAG-Epitope-Tagged Transforming Growth Factor Beta (TGF-beta) Protein
4/1/2001E-088-1999/06,949,624Cloning of the Human Nuclear Receptor Co-Repressor Gene
2/1/2001E-015-2000/0Antiprogestins with Partial Agonist Activity
2/1/2001E-237-2000/0RASS1: A Novel Tumor Suppressor Gene Activated by Ras to Promote Apoptosis
2/1/2001E-165-1999/0Potentiation of Antineoplastic Agents Using Sigma 2 Ligands
2/1/2001E-288-2000/06,706,867The ImmunoChip
2/1/2001E-186-2000/06,932,814Radio Frequency Probes for Tissue Treatment and Methods of Use
12/1/2000E-134-2000/07,101,541Utilization of Non-Viral Sequences for Minus-Strand DNA Transfer and Gene Reconstitution
12/1/2000E-090-2000/0
E-090-2000/1
E-227-2000/0
7,619,057Novel MHC Class II Restricted T Cell Epitopes from the Cancer Antigen, NY-ESO-1
and
MHC Class II Restricted CD4+ T Cell Epitopes From NY-ESO-1 Presented by DP
12/1/2000E-014-2000/06,600,018
7,223,853
Secreted Frizzled Related Protein, sFRP, Fragments and Methods of Use Thereof
12/1/2000E-196-2000/0Antitumor Immunity Elicited by Defensin-Tumor Antigen Fusions
12/1/2000E-194-2000/0Methods and Compositions of Viral Chemokine-Antigen Fusion Proteins as Vaccines for Tumors and AIDS
12/1/2000E-192-2000/0HCDS1 Kinase Activates Breast Tumor Suppressor BRCA1 and Promotes DNA Damage Repair
12/1/2000E-170-2000/07,141,661NAG-1: A Non-Steroidal Anti-Inflammatory Drug Related Gene Which Has Anti-Tumorigenic Properties
12/1/2000E-258-1999/06,521,635Inhibition of MXR Transport by Acridine Derivatives
12/1/2000E-259-2000/06,759,525Protein Kinase A and the Carney Complex
9/1/2000E-061-1999/0Polypeptides Comprising IL-6 Ligand Binding Receptor Domains and Related Nucleic Acids, Antibodies, Compositions and Methods
9/1/2000E-073-1999/06,737,511Receptor-Mediated Uptake of an Extracellular Bcl-XL Fusion Protein Inhibits Apoptosis
7/1/2000E-243-1999/0Fibroblast Growth Factor-5 (FGF-5) is a Tumor Associated T-cell Antigen for Human Renal Cell Cancer and Other Adenocarcinomas
7/1/2000E-265-1999/07,132,392Inhibition of Cell Motility
6/1/2000E-072-1999/06,765,104Transition Metal Complexes of N,N',N''-trialkyl-cis,cis-1,3,5-triaminocyclohexane and Related Compositions and Methods
4/1/2000E-201-1992/05,489,525Monoclonal Antibody Specific to Prostate Cells
4/1/2000E-194-1998/06,441,156
6,979,724
Calcium Channel Compositions and Methods of Use Thereof
9/1/1999E-232-1998/06,613,318
7,005,419
7,125,850
Methods For Identifying Modulators Of GADD45 Polypeptide Activity
9/1/1999E-216-1994/06,057,346Inhibition of Retroviral LTR Promoters by Calcium Response Modifiers
9/1/1999E-271-1998/0Methods For Treating Tumors Using Anti-Angiogenic Compounds
8/1/1999E-105-1999/07,226,991Phenylalanine Derivatives
8/1/1999E-124-1996/06,323,316
6,608,181
6,831,170
7,297,493
Fibroblast Growth Factor Receptor Activating Gene 1 (FRAG1), Related Proteins and Methods
7/1/1999E-071-1999/06,696,551
6,995,247
Ac-HEHA and Related Compounds, Methods of Synthesis and Methods of Use
6/1/1999E-058-1997/06,677,314
6,677,315
6,682,715
6,683,045
6,703,374
6,753,309
Nucleosides for Imaging and Treatment Applications
6/1/1999E-268-1998/06,423,696Modulation of N-Acetyl-Transferase to Improve Therapy and Prevent Cancer
6/1/1999E-019-1999/06,307,090Acylated Oligopeptide Derivatives Having Cell Signal Inhibiting Activity
5/1/1999E-137-1990/06,221,620Monoclonal Antibodies Specific for Human Thymidylate Synthase
4/1/1999E-221-1994/0Peptidomimetic Inhibitors of Cathepsin D and Plasmepsins I and II
4/1/1999E-157-1994/16,787,306
7,402,387
Method and Composition for Detecting Dihydropyrimidine Dehydrogenase Splicing Mutations
3/1/1999E-071-1991/25,645,988Method of Identifying and Using Drugs with Selective Effect Against Cancer Cells
3/1/1999E-301-1998/0
E-301-1998/1
E-301-1998/2
Combination Therapy With VIP Antagonists
2/1/1999E-082-1998/06,867,180
7,488,711
Use Of Calreticulin And Calreticulin Fragments To Inhibit Endothelial Cell Growth And Angiogenesis, And Suppress Tumor Growth
12/1/1998E-051-1995/05,702,892
5,824,520
Method of Inhibiting the Activity of an Intracellular Constituent
12/1/1998E-137-1996/06,326,466Double-Stranded RNA Dependent Protein Kinase Derived Peptides To Promote Proliferation Of Cells And Tissues In A Controlled Manner
11/1/1998E-385-1986/0Drug and Method for the Therapeutic Treatment of Primary Brain Tumors (Such As Intracranial Human Glioma, Astrocytomas, Medulloblastomas and Metastatic Tumors to the Central Nervous System)
9/1/1998E-190-1998/06,747,055
7,026,350
Water Soluble Drugs and Method of Preparing Same
7/1/1998E-013-1996/06,235,761Compound, Composition, and Method for Treating Cancer
10/1/1997E-113-1991/0raf Protein Kinase Therapeutics
10/1/1997E-018-1997/06,562,589
7,232,890
AIB-1, A Steroid Receptor Co-Activator Amplified In Breast And Ovarian Cancer
8/1/1997E-094-1997/07,358,347MEN1, The Gene For Multiple Endocrine Neoplasia Type 1
5/1/1997E-183-1996/0
E-219-1995/0
5,831,016
5,840,839
6,083,703
6,087,110
6,132,980
7,001,600
7,015,312
Novel Human Cancer Antigen of Tyrosinase-Related Proteins 1 and 2 and Genes Encoding Same
4/1/1997E-139-1994/05,637,323Method Of Mobilizing Pluripotent Hematopoietic Stem Cells And Accelerating Leukocyte Reconstitution With IL-7
1/1/1997E-051-1994/0
E-051-1994/1
5,674,492Method Of Preventing Or Treating Disease Characterized By Neoplastic Cells Expressing CD40
1/1/1997E-093-1995/05,830,755T-Cell Receptors And Their Use In Therapeutic And Diagnostic Methods
1/1/1997E-221-1995/06,951,917
7,501,501
MHC Class II-Restricted Melanoma Antigens And Their Use In Therapeutic Methods
12/1/1996E-347-1986/05,428,154Macrocyclic Chelates, and Methods of Use Thereof
11/1/1996E-088-1996/0Point Mutated ras Peptides for the Generation of CD8+ Cytotoxic T Lymphocytes
10/1/1996E-190-1990/05,484,889Plant Protein Useful For Treating Tumors And HIV Infection
8/1/1996E-039-1993/05,405,782A Detection Device and Quantification Method for Therapeutic Agents in Blood
8/1/1996E-226-1993/05,677,275
5,877,148
Treatment Of Cancer With Human Chorionic Gonadotropin
7/1/1996E-188-1992/05,837,477
5,948,409
5,958,712
6,900,024
T Cell Receptor Ligands, And Methods For Use
7/1/1996E-142-1993/05,578,566Peptide Antagonist Of Keratinocyte Growth Factor Activity
7/1/1996E-044-1991/26,566,098
7,605,127
Truncated Hepatocyte Growth Factor Variants
7/1/1996E-221-1989/0
E-221-1989/1
5,183,884
5,480,968
5,820,859
5,916,755
6,639,060
Novel Epidermal Growth Factor Receptor (ErbB-3) And Antibodies
4/1/1996E-184-1993/05,518,885
5,654,406
ERBB2 Promoter Binding Protein In Neoplastic Disease
4/1/1996E-131-1990/0
E-131-1990/1
5,731,301
5,808,038
Bistriazenes as Chemotherapeutic Agents
4/1/1996E-169-1993/05,990,088Method For Treatment Of Kaposi's Sarcoma (KS) By Antisense Oligonucleotides
4/1/1996E-024-1995/05,994,292Interferon-Inducible Protein 10 Is A Potent Inhibitor Of Angiogenesis
4/1/1996E-001-1989/05,532,144
6,090,795
Human Derived Monocyte Attracting Purified Peptide Products For Treating Human Infection And Neoplasms
4/1/1996E-053-1995/0
E-053-1995/1
5,716,788
5,763,216
A Gene Encoding a Human Reduced Folate Carrier (RFC) and Methods for the Treatment of Methotrexate-Resistant, Transport-Deficient Cancer Cells
1/1/1994E-253-1993/05,437,951
5,709,996
5,716,620
5,744,142
5,756,284
5,871,998
5,985,610
7,220,419
7,361,356
Self-Assembling Recombinant Papillomavirus Capsid Proteins
12/1/1993E-040-1993/05,833,986
5,863,739
Neutralizing Monoclonal Antibody To Human Alpha PDGF Receptors
1/1/1991E-493-1985/0
E-493-1985/1
3-Deazaneplanocin, Intermediates for It, and Antiviral Composition and Method of Treatment Using It
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