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Cancer - Research Materials:

DateRef. No.Patent No.Title
10/12/2009E-345-2008/0CXCR4 and CCR10 Expressing Cells: Useful for the Study of Cancer Cell Survival and Metastasis
9/17/2009E-005-2007/0Establishment of Two Cell Lines that Stably Express Luciferase for In Vivo Tracking
9/17/2009E-261-2007/0Mouse Embryonic Stem Cell-based Functional Assay to Evaluate Mutations in BRCA2
8/11/2009E-058-2009/0Development of a New Carbohydrate Antibody to GalNac1-3Gal
7/29/2009E-229-2009/0A Tumorigenic MEF/3T3 Tet-Off Mouse Fibroblast Cell Line Stably Transfected with a T7-Tagged Srp20 Expression Construct (pJR17)
7/17/2009E-216-2009/0High Diversity/High Affinity Domain Antibody Library
6/11/2009E-164-2007/0Compounds Binding to the N-Terminal Domains of STAT Proteins as Therapeutic Agents
6/8/2009E-171-2009/0Improved Antibodies Against ErbB4/Her4
5/28/2009E-101-2006/0Tools to Identify Candidates for Effective Cancer Therapy: Antibodies to Human Asparagine Synthetase
5/28/2009E-162-2004/0Mouse Model with Targeted Disruption of the Neurofibromatosis Type-1 (Nf1) Gene
5/15/2009E-129-2009/0A549 Cells: A Well-Characterized Lung Carcinoma Cell Line Utilized for a Variety of Scientific Studies, including Adenovirus Production and Testing
5/4/2009E-154-2004/0Creation and Characterization of Carcinogen-Altered Mouse Epidermal Cell Lines
5/4/2009E-159-2005/0DU145 Camptothecin (CPT)-Resistant Cell Line
5/4/2009E-241-2005/0Transgenic Mice in which the Gene for MCP-1 is Deleted
5/4/2009E-053-2006/0Polyclonal Antibody Against Bloom's Syndrome Protein (BLM) for Research and Diagnostic Use
5/4/2009E-193-1997/06,555,367Targeted Recombinant Adenoviral Vectors
2/25/2009E-245-2003/0Glutathione S-transferase Clones for Members of the Ubiquitin-Dependent Protein Degradation Pathway
1/1/2009E-274-2008/0Monoclonal Antibodies to the Tumor-Specific Antigen, Human ROR1
12/1/2008E-003-2008/0A Novel, Non-Invasive and Therapeutically Useful High Throughput Technique to Isolate Highly Enriched Tumor Reactive Lymphocytes from Peripheral Blood - Potential Use in Adoptive Immunotherapy
11/1/2008E-174-2008/0Therapeutic Targeting of CSN5, a Negative Regulator of p53 and p27, in Human Hepatocellular Carcinoma
9/1/2008E-111-1991/0
E-111-1991/1
5,585,462
6,074,842
Human Perilipin Proteins
9/1/2008E-163-2007/0Bifunctional Compounds that Bind to Hormone Receptors
7/1/2008E-091-2008/0Method for Detection and Quantification of PLK1 Expression and Activity
5/1/2008E-080-2008/0Human and Improved Murine Monoclonal Antibodies Against CD22
5/1/2008E-079-2008/0Human Monoclonal Antibody Against Mesothelin
5/1/2008E-281-2007/0Multicolored Fluorescent Cell Lines for High-Throughput Angiogenesis and Cytotoxicity Screening
5/1/2008E-316-2007/0Method of Inhibiting ABCG2 and Related Treatments
9/1/2007E-272-1998/06,790,948
7,431,926
Tumor Suppressor Genes
9/1/2007E-153-1998/07,256,256Peptide Inhibitor of Cyclin Dependent Kinase 4 (CDK4) Derived from MyoD
8/1/2007E-068-1998/06,685,933
7,235,232
Interferon Alpha Hybrids
5/1/2007E-281-2002/07,193,053Leu574 of HIF-1alpha as a Molecular Basis for Therapeutic Application
5/1/2007E-307-2004/1Aminoalkyl Substituted O6-Benzylguanine Derivatives as Inactivators of O6-Alkylguanine-DNA Alkyltransferase and Adjuvants for Chemotherapy
1/1/2007E-293-2006/0Megakaryocyte Potentiation Factor as a New Serum Tumor Marker for Mesothelioma
12/1/2006E-330-2003/0Antisera to Detect Phosphorylated Phosphoinositide-Dependent Kinase 1 (PDK-1)
12/1/2006E-014-2007/0Peptide and Peptidomimetic Inhibitors of Smoothened Protein as Anti-neoplastic Agents
6/1/2006E-336-2005/0Novel Human IGF-1 Specific IGF-I and IGF-II Cross-Reactive Human Monoclonal Antibodies as Potential Anti-tumor Agents
3/1/2006E-262-1999/17,459,536Monoclonal Antibodies Which Specifically Bind to the Ligand Hepatocyte Growth Factor (HGF) and are Useful in the Treatment of Cancer
12/1/2005E-323-2003/07,589,181Minimally Immunogenic Variants of SDR-Grafted Humanized Antibody CC49 and Their Use
12/1/2005E-264-2005/0Mouse Polyclonal Antibodies to KAI1
10/1/2005E-327-2005/0NIH3T3 Cell Lines Carrying c-Met Mutations Including G3906A, G3522A, G3810T, T3936C, T3936G, T3997C, C3528T, C3564G, C3831G, A3529T, and T3640C
10/1/2005E-274-2005/0Murine Mast Cell Line Useful for Toxicity and Immunopotency Screens
10/1/2005E-167-1997/07,153,866The Use of Nitroxides in the Prophylactic and Therapeutic Treatment of Cancer Due to Genetic Defects
9/1/2005E-327-2004/0A New Approach Toward Macrocyclization of Peptides
9/1/2005E-144-2005/0Soluble Fragments of the IGF1R Ectodomain
9/1/2005E-095-2000/2Amelioration of Inflammatory Arthritis Targeting the Pre-ligand Assembly Domain (PLAD) of Tumor Necrosis Factor Receptors
9/1/2005E-087-1996/0Heterologous Boosting Immunizations
8/1/2005E-168-2005/0Monoclonal Antibody to the Protein NCOA6 (also called ASC-2, AIB-3)
7/1/2005E-075-2004/2Methods for the Identification and Use of Compounds Suitable for the Treatment of Drug Resistant Cells
6/1/2005E-339-2004/0Framework Residue Substituted Humanized COL-1 Antibodies and Their Use
5/1/2005E-351-2004/0Antibodies to Rheb, a Ras-Related Protein
5/1/2005E-245-2004/0Methods of Reducing the Activity and Concentration of an Eph Receptor Tyrosine Kinase
5/1/2005E-135-2004/0Retinal Pigment Epithelial Cells Immortalized with TERT and Expressing the Adenoviral E1A Oncoprotein
4/1/2005E-265-1994/0
E-265-1994/1
6,255,105
6,342,392
6,737,251
7,067,635
Nucleotide and Deduced Amino Acid Sequences of a New Tumor Gene, Int6
4/1/2005E-324-2001/2Selections of Genes and Methods of Using the Same for Diagnosis and for Targeting the Therapy of Select Cancers
4/1/2005E-156-2004/0Chinese Hamster Ovary Cells Resistant to Colcemid with Altered beta-Tubulin
3/1/2005E-105-2004/0
E-105-2004/1
Minimally Immunogenic Germline Sequence Variants of COL-1 Antibody and Their Use
3/1/2005E-166-2001/07,557,196HGC-1, A Gene Encoding a Member of the Olfactomedin-Related Protein Family
3/1/2005E-108-2004/0
E-234-2003/0
Methods for Identifying, Diagnosing, and Predicting Survival of Lymphomas
1/1/2005E-017-2005/0Methods and Composition for Development of Preclinical Testing of Anticancer Therapies Using Transgenic Animals
1/1/2005E-123-2001/0
E-124-2001/1
7,247,615Peptide Agonists of Prostate-Specific Antigen and Uses Thereof
9/1/2004E-243-2004/0Vectors for Wild-Type DDR1b or DDR1b Mutant, and Production of THP-1 Cell Line Expressing Two DDR1 Isoforms, DDR1a and DDR1b
8/1/2004E-266-2004/0Mouse Model of PRKAR1A Down-Regulation
6/1/2004E-112-1994/05,652,223
5,981,712
6,790,936
DNA Encoding CAI Resistance Proteins and Uses Thereof
5/1/2004E-131-2004/0AT8, a Hybridoma Cell Line Producing a Monoclonal Antibody (MAb) Specific for Ly49G, a Mouse Natural Killer (NK) Cell Receptor
3/1/2004E-107-2004/0Specific Antibodies to the Lymphatic Endothelial Cell Specific Hyaluronic Acid Receptor, LYVE-1
11/1/2003E-008-2001/07,598,077Compositions and Methods for Enhancing Differential Gene Expression
6/1/2003E-091-2002/07,329,502Zap70 Protein Expression as a Marker for Chronic Lymphocytic Leukemia (CLL)
5/1/2003E-161-2003/0Flp-in T-Rex Jurkat Cell Line
4/1/2003E-191-2002/07,521,475Chondropsin-Class Antitumor V-ATPase Inhibitor Compounds, Compositions and Methods of Use Thereof
2/1/2003E-251-2000/0Telomerase Immortalized Hepatocyte Cell Lines
2/1/2003E-340-2002/04G10, a Monoclonal Antibody Against the Chemokine Receptor CXCR4, Raised Against a Synthetic Peptide of 38 Residues in Length Derived from the N-terminal Sequence of CXCR4
4/1/2002E-099-2001/0Mitochondrial Topoisomerase I
12/1/2001E-295-2001/0Imaging of Extracellular Proteases in Cells Using Mutant Anthrax Toxin Protective Antigens
11/1/2001E-261-1998/06,969,614Methods and Devices for Isolation and Analysis of Cellular Protein Content
8/1/2001E-264-2001/0H2,056A Mouse Model of von Hippel-Lindau Disease
5/1/2001E-203-1994/05,693,779Production and Use of Anti-Dorsalizing Morphogenetic Protein
4/1/2001E-149-2000/06,756,215Biologically Active FLAG-Epitope-Tagged Transforming Growth Factor Beta (TGF-beta) Protein
3/1/2001E-336-1987/15,693,778ARG, A Human Gene Related to but Distinct from ABL Proto-Oncogene
12/1/2000E-014-2000/06,600,018
7,223,853
Secreted Frizzled Related Protein, sFRP, Fragments and Methods of Use Thereof
9/1/2000E-142-1999/06,362,317
6,884,873
Anti-H2A Antibody and Method for Detecting DNA Double-Stranded Breaks
9/1/1999E-216-1994/06,057,346Inhibition of Retroviral LTR Promoters by Calcium Response Modifiers
8/1/1999E-011-1998/06,849,417
7,442,543
Mammalian Selenoprotein Differentially Expressed in Tumor Cells
7/1/1999E-077-1999/06,623,960
7,524,939
Monoclonal Antibodies Specific And Inhibitory To Human Cytochrome P450 2C8, 2C9, 2C18 And 2C19 - New Avenues For Drug Discovery
6/1/1999E-032-1995/05,650,627Sensitive Assay for Measuring Gallium Levels in Body Tissues and Fluids
4/1/1999E-157-1994/16,787,306
7,402,387
Method and Composition for Detecting Dihydropyrimidine Dehydrogenase Splicing Mutations
3/1/1999E-071-1991/25,645,988Method of Identifying and Using Drugs with Selective Effect Against Cancer Cells
10/1/1998E-150-1998/06,323,325Agents That Bind To And Inhibit Cytochrome P450 2A6
10/1/1998E-122-1998/06,335,428Agents That Bind To And Inhibit Human Cytochrome P450 1A2
10/1/1997E-246-1988/05,211,657Laminin A Peptides
5/1/1997E-046-1997/06,060,253Agents That Bind To And Inhibit Human Cytochrome P450 2D6
1/1/1997E-160-1992/15,487,979
5,717,067
5,872,219
eps15, Substrate For The Epidermal Growth Factor Receptor Kinase
11/1/1996E-185-1995/05,939,530Inhibitory And Non-Inhibitory Antigen Binding Polypeptides Against Human P450 Enzymes
7/1/1996E-094-1994/07,070,972
7,488,808
Janus Family Kinases (JAK) And Identification Of Immune Modulators
7/1/1996E-221-1989/0
E-221-1989/1
5,183,884
5,480,968
5,820,859
5,916,755
6,639,060
Novel Epidermal Growth Factor Receptor (ErbB-3) And Antibodies
4/1/1996E-029-1990/0
E-029-1990/1
5,403,926
5,702,907
5,811,262
Hepatocellular Carcinoma Oncogene
11/1/1994E-005-1993/05,532,348
5,914,389
E6-Associated Protein And Methods Of Use
4/1/1994E-116-1992/05,569,602The First Immortalized Kaposi's Sarcoma Cell Line
1/1/1994E-253-1993/05,437,951
5,709,996
5,716,620
5,744,142
5,756,284
5,871,998
5,985,610
7,220,419
7,361,356
Self-Assembling Recombinant Papillomavirus Capsid Proteins
12/1/1993E-040-1993/05,833,986
5,863,739
Neutralizing Monoclonal Antibody To Human Alpha PDGF Receptors
2/1/1992E-193-1990/05,321,014Molecular Encapsulation and Delivery of Alkanes to Living Mammalian Cells for Risk Assessment and Pharmaceutical Applications
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